Results 161 to 170 of about 10,171,198 (336)

Considerations for drug trials in hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant, Matthias Schmitt, Anna B. Reid, Clifford J. Garratt, William G. Newman, Aneil Malhotra, Rhys Beynon, Masliza Mahmod, Betty Raman, Robert M. Cooper, Dana Dawson, Thomas Green, Sanjay K. Prasad, Anvesha Singh, Susanna Dodd, Hugh Watkins, Stefan Neubauer, Christopher A. Miller   +17 more
wiley   +1 more source

Impact of air quality policy scenarios on pollution inequalities in a UK metropolitan area. [PDF]

Front Public Health
Hodgson JR, Bartington S, Shi Z, Bloss WJ.   +3 more
europepmc   +1 more source

8 Blood-fed females of Culex pipiens complex collected at Zoos in Metropolitan area(Contributed Papers,Proceedings of the 57th Annual Meeting of Eastern Region)

, 2006
Keiko Sawabe, Yukiko Higa, Y. TSUDA, Shinji Kasai, Haruhiko Isawa, Koichi Murata, Yukita Sato, N. Nagatsuka, Ryōji Matsumoto, M Ueda, Tokiko Endo   +10 more
openalex   +2 more sources

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

A high-resolution geospatial dataset of cyclist-involved crashes and segmented cycling infrastructure in the Guadalajara metropolitan area (2015-2024). [PDF]

Data Brief
Domínguez-Báez CA, Luna-García H, Celaya-Padilla JM, Mendoza-González R, Acra-Despradel C, Villalba-Condori KO.   +5 more
europepmc   +1 more source

Validation of self reported physical activity in adults of Pamplona Metropolitan Area (SPAIN) [PDF]

, 2014
Rosario Orzanco-Garralda, Francisco Guillén‐Grima, Inés Aguinaga-Ontoso   +2 more
openalex   +1 more source

Rainfall intensity in the Genoa Metropolitan Area: secular variations and consequences

, 2018
F. Acquaotta, F. Faccini, S. Fratianni, G. Paliaga, A. Sacchini   +4 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Spatial pattern assessment of Aedes mosquito bite risk in a subtropical metropolitan area: A case study in Shenzhen. [PDF]

PLoS Negl Trop Dis
Lin L, He Y, Guang X, Xiang L, Kong D, Diao K, Wang H, Zhu B.   +7 more
europepmc   +1 more source

An Analysis of Dwelling Relocation among Sectors in Major Metropolitan Areas

, 1991
Kenichi Furuta, Mahito NAKAZONO, Takeshita Terukazu   +2 more
openalex   +2 more sources