IMPROVEMENT OF THE DISSOLUTION PROFILE OF SIMVASTATIN TABLETS WITH THE ADDITION OF CREMOPHOR-EL USING WET GRANULATION METHOD [PDF]
, 2021 Objective: Simvastatin is a drug used as a first-line anti-cholesterol in the treatment of dyslipidemia. Low solubility will affect its ability to penetrate the digestive tract membrane and will affect the amount of drug levels in the plasma.
GUSTAMAN, FIRMAN +4 more
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Effects of fatty acids upon LDL catabolism in cultured cells [PDF]
, 1986 Imperial Users ...
Gavigan, S. J. P., Gavigan, S. J. P.
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Tigliane diterpenoids: isolation, chemistry and preliminary biosynthetic studies of a medicinal relevant class of natural compounds [PDF]
, 2020 Tiglianes are a class of polycyclic diterpenoids, densely functionalized, isolated from Euphorbiaceae and Thymelaceae family. Despite their extensive use in biomedical research, and their potent and unique biological profile, phorboids are still largely ...
Gaeta, Simone
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Monoterpene metabolism of mentha and its cell cultures [PDF]
, 1985 Imperial Users ...
Hudson, Michael John +1 more
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Development of similarity measures from graph-structured bibliographic metadata: An application to identify scientific convergence [PDF]
Scientific convergence is a phenomenon where the distance between hitherto distinct scientific fields narrows and the fields gradually overlap over time. It is creating important potential for research, development, and innovation.
Bröring, S. +6 more
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Effects of inhibitors of proteins in the ras signaling pathway on the formation of filaments in Ccandida Albicans, 2004 [PDF]
Candida albicans is a fungus that may cause mild to fatal infections in people with compromised immune systems. Patients undergoing chemotherapy or radiation therapy as a result of cancer, or those infected with AIDS, frequently develop Candida ...
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Studies in the biosynthesis of triterpenoids [PDF]
, 1968 Imperial Users ...
Harrison, David Miles +1 more
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Pharmaceutical Chemistry of Molecular Therapeutics [PDF]
This project is made possible with funding by the Government of Ontario and through eCampusOntario’s support of the Virtual Learning Strategy. To learn more about the Virtual Learning Strategy visit: https://vls.ecampusontario.ca.1.
D. de Araujo, Elvin +3 more
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A radical cascade approach to the skeleton of α−Cyclopiazonic Acid [PDF]
, 2012 3-Nitrophthalic acid 2.04 was transformed into 2.10 in 38% yield. Vinylglycine derivative was synthesised from D-Methionine 2.12 in 42% yield. (For image see abstract in pdf) Compounds 2.10 and 2.16 were coupled using Grubbs’ 2nd generation ...
Craft, Russell S
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Ultrastructural Localization of Solanidine in Potato Tubers [PDF]
, 1980 Solanine, the green substance in potato, Solanum tuberosum L., tubers, is a toxic glycoalkaloid that is a potential human health hazard. To control the formation of this glycoalkaloid a greater understanding of its site of synthesis is needed.
Han, Shau-Ron
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