Results 41 to 50 of about 26,010 (266)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Segregation of Yttrium at the Mg/MgO Interface in an Mg-0.5Y Alloy

open access: yesActa Materialia, 2023
Supplementary materials are available online at https://www.sciencedirect.com/science/article/pii/S1359645423004780#sec0023 .
Wang, S.   +4 more
openaire   +3 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Research advances of magnesium and magnesium alloys globally in 2024

open access: yesJournal of Magnesium and Alloys
Research on magnesium (Mg) alloys still remains a prominent and expanding field in recent years. The Web of Science Core Collection database documented 4898 published articles on the topic, highlighting a sustained and growing interest.
Yuan Yuan   +9 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Mechanical properties of advanced mg alloys

open access: yesCommunications, 1999
This paper describes the tensile strength of Mg alloys determined at room temperature and creep. The deformation mechanisms are discussed.
Pavel Lukáč   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Chemically stable TMOx@Ti-MgO (TM = Mn and Cu) catalyst enhanced De/hydrogenation kinetics of Mg/MgH2

open access: yesJournal of Magnesium and Alloys
Ti-based catalysts have been identified to be efficient in enhancing hydrogenation and dehydrogenation (de/hydrogenation) kinetics of Mg/MgH2. However, their catalytic activity is constrained by the strong Ti‒H bond and chemical instability.
Haotian Guan   +4 more
doaj   +1 more source

Possibilities and Limitations of Scanning Electrochemical Microscopy of Mg and Mg Alloys [PDF]

open access: yesCorrosion, 2014
Magnesium (Mg) and its alloys undergo corrosion at high rates in aqueous electrolytes of essentially any concentration, releasing copious amounts of hydrogen (H2) into the electrolyte, thereby making conventional scanning electrochemical microscopy (SECM) measurements difficult upon Mg.
Souto, Ricardo Manuel   +3 more
openaire   +3 more sources

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