Results 51 to 60 of about 44,554 (315)
, 2005 Al-Mg-Cu-Mn alloys have been developed for the packaging industry, in which large cold-working deformations are normally applied that can produce high dislocation densities.
Zhu, Z., Starink, M.J., Wang, S.C.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Processing of metal matrix composites under external fields and their application as grain refiner [PDF]
, 2014 In an attempt to develop an efficient grain refiner by application of external fields, aluminium-based metal matrix composite Al- Mg-Ti/TiB 2, has been processed by mechanical stirring and treated by external field such as ultrasonication.
Vadakke Madam, S +12 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Control of Magnesium Alloy Corrosion through the Use of Engineered Intermetallics [PDF]
, 2014 The low density and high relative strength of Mg alloys means they can offer engineering benefits over steels or Al alloys. However, the susceptibility of Mg alloys to corrosion has limited their exploitation and restricted their use to more benign ...
Pidcock, Andrew
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Research advances of magnesium and magnesium alloys globally in 2024
Journal of Magnesium and AlloysResearch on magnesium (Mg) alloys still remains a prominent and expanding field in recent years. The Web of Science Core Collection database documented 4898 published articles on the topic, highlighting a sustained and growing interest.
Yuan Yuan +9 more
doaj +1 more source
Solidification behaviour of magnesium alloys [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Magnesium alloys have been extensively used for structural and functional applications due to their low densities.
Jiang, Bo
core
Biodegradation and Mechanical Integrity of Magnesium and Magnesium Alloys Suitable for Implants
, 2013 This book chapter deals with the fundamental aspects of corrosion of magnesium based alloys in bodily fluids and reviews the various techniques that can be used to tune their degradation rate.
Suriñach, Santiago +9 more
core +1 more source