Results 71 to 80 of about 3,790,194 (348)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Shear enhanced heterogeneous nucleation in some Mg- and Al- alloys [PDF]
, 2009 Intensive shearing was applied to alloy melts at temperatures above their liquidus by using a twinscrew mechanism. The sheared melt was then cast into a TP1 mould for microstructural examination.
Fan, Z +7 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Tensile properties of high strength cast Mg alloys at room temperature: A review [PDF]
China Foundry, 2014 As most Mg alloy products are now produced by a casting process, the development of high strength cast Mg alloys can promote their further applications and has already become one of the hot research areas of Mg alloys.
Fu Penghuai, Peng Liming, Jiang Haiyan
doaj
Microstructure and strength of metals processed by severe plastic deformation [PDF]
, 2006 The microstructure of f.c.c. metals (Al, Cu, Ni) and alloys (Al-Mg) processed by severe plastic deformation (SPD) methods is studied by X-ray diffraction line profile analysis.
Chinh, Nguyen Quang +3 more
core
, 2012 A model for the thermodynamics of and strengthening due to Cu–Mg co-clusters in Al–Cu–Mg based alloys is analysed and tested. The formulation uses a single interaction enthalpy between dissimilar alloying elements (e.g.
Starink, M. J.
core +1 more source
Grain boundary segregation in UFG alloys processed by severe plastic deformation [PDF]
, 2012 Grain boundary segregations were investigated by Atom Probe Tomography in an Al-Mg alloy, a carbon steel and Armco\trademark Fe processed by severe plastic deformation (SPD).
Enikeev, Nariman +5 more
core +3 more sources
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
The influences of holmium on the solidification, microstructure and mechanical properties of elektron 21 magnesium alloy [PDF]
, 2018 The solidification parameter of Elektron 21 magnesium alloys with various Ho concentrations were investigated using computer-aided cooling curve thermal analysis system, and the solidification microstructure and phase constitution of the investigated ...
Shahizan, Nurul Raihan
core
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source