Results 51 to 60 of about 21,152 (221)

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane   +4 more
wiley   +1 more source

Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic

open access: yesScientific Reports, 2021
To investigate the prevalence of meibomian gland dysfunction (MGD) in patients presenting with subjective dry eye-related symptoms at their first-time consultation in a Norwegian specialized ocular surface clinic. Additionally, to explore the accuracy of
Reza A. Badian   +7 more
doaj   +1 more source

Meibomian Glands and Tear Film Findings in Type 2 Diabetic Patients: A Cross-Sectional Study

open access: yesFrontiers in Medicine, 2022
BackgroundThe characteristics of the meibomian gland and tear film in patients with type 2 diabetes (T2D) with different glycemic control levels and diabetic durations remain largely unexplored. This study aimed to identify the association of dry eye and
Huping Wu   +19 more
doaj   +1 more source

Maize Yield, Water Productivity and Economic Analysis Under Different Irrigation and Nitrogen Management Strategies Using Field Data and CERES‐Maize Model

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT There is limited integrated evaluation of nitrogen (N) and irrigation management strategies for improving maize yield and productivity using crop models. The effects of N and irrigation on maize yield and productivity under centre pivot (CPI) and subsurface drip irrigation (SDI) using the CERES‐Maize model were investigated. N treatments were (
Ebrahim Amiri   +2 more
wiley   +1 more source

The correction of conjunctivochalasis using high-frequency radiowave electrosurgery improves dry eye disease

open access: yesScientific Reports, 2021
We aimed to determine the clinical impact of conjunctivochalasis (CCh) and its correction using high-frequency radiowave electrosurgery (HFR-ES), for signs and symptoms of dry eye disease (DED).
Yong Woo Ji   +6 more
doaj   +1 more source

Gene Therapy for Amino Acid Decarboxylase Deficiency: Clinical and Imaging Outcomes in a French Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer   +27 more
wiley   +1 more source

Quantitative analysis of morphological and functional features in Meibography for Meibomian Gland Dysfunction: Diagnosis and Grading

open access: yesEClinicalMedicine, 2021
Background: To explore the performance of quantitative morphological and functional analysis in meibography images by an automatic meibomian glands (MGs) analyser in diagnosis and grading Meibomian Gland Dysfunction (MGD).
Yuqing Deng   +8 more
doaj   +1 more source

Cross‐Cohort Evidence Links KCNJ6 rs702859 to Impulsive–Compulsive Phenotypes in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Impulse control disorders (ICDs) and related compulsive behaviors (CBs) are frequent non‐motor complications of Parkinson's disease (PD) with a probable genetic contribution. Objective To investigate whether genetic variants involved in reward and punishment processing are associated with impulsive–compulsive phenotypes in PD ...
Sergio García‐Díaz   +21 more
wiley   +1 more source

The Effect of Smoking onmeibomian gland dysfunction (MGD) Parameters.

open access: yes, 2016
The Effect of Smoking onmeibomian gland dysfunction (MGD) Parameters.
Wei Li (7081)   +6 more
core   +1 more source

Dry Eye Disease Associated with Meibomian Gland Dysfunction: Focus on Tear Film Characteristics and the Therapeutic Landscape

open access: yesOphthalmology and Therapy, 2023
Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum secretion and/or a change in meibum composition that results in the disruption of the tear ...
John D. Sheppard, Kelly K. Nichols
doaj   +1 more source

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