Results 131 to 140 of about 20,586 (243)

Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model

Cell Reports, 2015
Abnormal metabotropic glutamate receptor 5 (mGluR5) function, as a result of disrupted scaffolding with its binding partner Homer, contributes to the pathophysiology of fragile X syndrome, a common inherited form of intellectual disability and autism ...
Weirui Guo, Laura Ceolin, Katie A. Collins, Julie Perroy, Kimberly M. Huber   +4 more
doaj   +1 more source

Transport of BMAA into Neurons and Astrocytes by System x\u3csub\u3ec\u3c/sub\u3e- [PDF]

, 2018
The study of the mechanism of β-N-methylamino-l-alanine (BMAA) neurotoxicity originally focused on its effects at the N-methyl-d-aspartate (NMDA) receptor. In recent years, it has become clear that its mechanism of action is more complicated.
Albano, Rebecca, Lobner, Doug
core   +1 more source

Reduced astrocytic mGluR5 in the hippocampus is associated with stress-induced depressive-like behaviors in mice

, 2022
Cong Liu, Tian‐Qi Yang, Yudong Zhou, Yi Shen   +3 more
openalex   +1 more source

MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium–Pilocarpine Model of Epilepsy [PDF]

, 2022
A. V. Dyomina, Anna A. Kovalenko, Maria V. Zakharova, Tatyana Y. Postnikova, Alexandra V. Griflyuk, Ilya V. Smolensky, Irina Antonova, Aleksey V. Zaitsev   +7 more
openalex   +1 more source

mGluR5 Regulates Glutamate-Dependent Development of the Mouse Somatosensory Cortex [PDF]

, 2008
Lasani S. Wijetunge, Sally M. Till, Thomas H. Gillingwater, C.A. Ingham, Peter C. Kind   +4 more
openalex   +1 more source

Pharmacological and Anatomical Evidence for an Interaction Between mGluR5- and GABAA α1-Containing Receptors in the Discriminative Stimulus Effects of Ethanol [PDF]

, 2004
Joyce Besheer, Clyde W. Hodge
openalex   +1 more source

Characterizing the modulation of mGluR5 in a 6-OHDA-induced rat model of Parkinson's disease [PDF]

, 2008
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2008.Includes bibliographical references (leaves 26-27).MicroPET imaging studies were conducted to investigate the role of metabotropic glutamate subtype-5 ...
Lamb, Peter (Peter Alexander John)
core  

Deletion of Densin-180 Results in Abnormal Behaviors Associated with Mental Illness and Reduces mGluR5 and DISC1 in the Postsynaptic Density Fraction [PDF]

, 2011
Holly J. Carlisle, Tinh N. Luong, Andrew G. A. Medina-Marino, Leslie T. Schenker, Eugenia M. Khorosheva, Tim Indersmitten, Keith M. Gunapala, Andrew D. Steele, Thomas J. O’Dell, Paul H. Patterson, Mary B. Kennedy   +10 more
openalex   +1 more source

Anti-metabolic glutamate receptor 5 encephalitis with gangliocytoma: a case and review of the literature

BMC Neurology
Background There are very limited reports on anti-metabolic glutamate receptor5 (mGluR5) encephalitis, especially lacking of pediatric research. The disease was mostly accompanied by tumors, mainly Hodgkin's lymphoma.
Kaili Shi, Huimin Zhao, Ying Li, Xiaojing Li, Wenxiong Chen   +4 more
doaj   +1 more source

p11 regulates the surface localization of mGluR5 [PDF]

Molecular Psychiatry, 2015
K-W, Lee, L, Westin, J, Kim, J C, Chang, Y-S, Oh, B, Amreen, J, Gresack, M, Flajolet, D, Kim, A, Aperia, Y, Kim, P, Greengard   +11 more
openaire   +2 more sources