Over the last few decades, scientists' attention has shifted from neuronal to non-neuronal cells to explain the mechanisms at the basis of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Matilde Balbi +18 more
doaj +1 more source
The RNA Binding Protein TLS Is Translocated to Dendritic Spines by mGluR5 Activation and Regulates Spine Morphology [PDF]
Ritsuko Fujii +8 more
openalex +1 more source
Astrocytes Control Neuronal Excitability in the Nucleus Accumbens
Though accumulating evidence shows that the metabotropic glutamate receptor 5 (mGluR5) mediates some of the actions of extracellular glutamate after cocaine use, the cellular events underlying this action are poorly understood.
Tommaso Fellin +2 more
doaj +1 more source
The Effects of N-Acetylcysteine on the Rat Mesocorticolimbic Pathway: Role of mGluR5 Receptors and Interaction with Ethanol [PDF]
Sandra Fernández‐Rodríguez +5 more
openalex +1 more source
The BH4 domain of Bcl-XL rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals [PDF]
Collective evidence indicates that motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is non-cell-autonomous and requires the interaction with the neighboring astrocytes.
Aronica, Eleonora +8 more
core
Inhibition of Group I Metabotropic Glutamate Receptors (mGluR1 and mGluR5) Protects Against Prion-Induced Toxicity [PDF]
Despoina Goniotaki
openalex +1 more source
mGluR5, CB1 and neuroprotection
Carvalho, Toniana G. +2 more
openaire +2 more sources
Metabotropic Glutamate 5 Receptor (mGluR5) Antagonists Decrease Nicotine Seeking, But Do Not Affect the Reinforcement Enhancing Effects of Nicotine [PDF]
Matthew I. Palmatier +4 more
openalex +1 more source
Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5) [PDF]
Laura T. Haas +2 more
openalex +1 more source
Chronic Inflammatory Pain Impairs mGluR5-Mediated Depolarization-Induced Suppression of Excitation in the Anterior Cingulate Cortex [PDF]
Baolin Guo +10 more
openalex +1 more source

