Results 1 to 10 of about 229 (60)

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

Nature Communications, 2020
Quanhua Mu, Zhaoshi Bao, Jason K Sa
exaly  

O6-Methylguanine-DNA Methyltransferase (MGMT): Challenges and New Opportunities in Glioma Chemotherapy

Frontiers in Oncology, 2020
Wei Yu, Qichun Wei, Anwen Shao
exaly  

MGMT testing—the challenges for biomarker-based glioma treatment

Nature Reviews Neurology, 2014
Wolfgang Wick, Michael Weller, Martin J B Van Den Bent   +2 more
exaly  

A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma

Nature Communications, 2018
Minjie Zhang, Haiyun Gan, Heping Wang
exaly  

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

Nature Communications, 2015
Malin Wickström, , Raul Calero
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The prognostic value of MGMT promoter methylation in glioblastoma: A meta‐analysis of clinical trials

Journal of Cellular Physiology, 2018
Maryam Moradi Binabaj, Afsane Bahrami, Seyed Mahdi Hassanian   +2 more
exaly  

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Acta Neuropathologica, 2012
Pierre Bady, Jocelyne Bloch, Christine Marosi   +2 more
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Advances in the molecular genetics of gliomas — implications for classification and therapy

Nature Reviews Clinical Oncology, 2016
Guido Reifenberger, Hans-Georg Wirsching, Christiane B Knobbe-Thomsen   +2 more
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Acquired temozolomide resistance in MGMT-deficient glioblastoma cells is associated with regulation of DNA repair by DHC2

Brain, 2019
Guanglong Huang, Hai Wang, Ziyang Chen
exaly  

MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

DNA Repair, 2007
Bernd Kaina, Markus Christmann, Wynand P Roos   +2 more
exaly