Autophagy as a Potential Therapy for Malignant Glioma [PDF]
Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms.
Angel Escamilla-Ramírez +10 more
doaj +2 more sources
Calidad de vida de pacientes con tumores cerebrales: panorama actual [PDF]
El presente artículo revisa el panorama actual de la calidad de vida en el área de la salud, y de forma específica en tumores cerebrales primarios. Se inicia con una definición y clasificación de los tumores cerebrales de acuerdo a diferentes variables ...
María Eugenia Olivares +3 more
doaj +2 more sources
Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential [PDF]
Breast milk is a fluid of vital importance during the first stages of life of the newborn since, in addition to providing nutrients, it also contains cells and molecules of the immune system, which protect the neonate from infection and, at the same time,
Alba Soledad Aquino-Domínguez +12 more
doaj +2 more sources
Lrba participates in the differentiation of IgA+ B lymphocytes through TGFβR signaling [PDF]
IntroductionLrba is a cytoplasmic protein involved in vesicular trafficking. Lrba-deficient (Lrba-/-) mice exhibit substantially higher levels of IgA in both serum and feces than wild-type (WT) mice.
José Mizael Flores-Hermenegildo +11 more
doaj +2 more sources
Preradiotherapy MR Imaging: A Prospective Pilot Study of the Usefulness of Performing an MR Examination Shortly before Radiation Therapy in Patients with Glioblastoma. [PDF]
Background and purpose: Current protocols in patients with glioblastoma include performing an MR examination shortly after surgery and then 2-6 weeks after ending concomitant chemoradiotherapy. The assessment of this first postradiotherapy examination is
Majós C +8 more
europepmc +3 more sources
Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma. [PDF]
Glioblastoma (GBM) is the most common and devastating primary brain tumor. The presence of cancer stem cells (CSCs) has been linked to their therapy resistance.
Hernández-SanMiguel E +10 more
europepmc +5 more sources
Controlled release microspheres loaded with BMP7 suppress primary tumors from human glioblastoma. [PDF]
Glioblastoma tumor initiating cells are believed to be the main drivers behind tumor recurrence, and therefore therapies that specifically manage this population are of great medical interest.
González-Gómez P +7 more
europepmc +6 more sources
Bevacizumab for the treatment of glioblastoma. [PDF]
Glioblastoma (GBM) or grade IV glioma is the most common primary brain tumor in adults. Standard treatment median overall survival (OS) is only 14-15 months and less than 10% of patients will survive 5 years after diagnosis.
Gil-Gil MJ, Mesia C, Rey M, Bruna J.
europepmc +2 more sources
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth. [PDF]
Glioblastomas (GBMs) are very aggressive tumors that are resistant to conventional chemo- and radiotherapy. New molecular therapeutic strategies are required to effectively eliminate the subpopulation of GBM tumor-initiating cells that are responsible ...
Pozo N +10 more
europepmc +3 more sources
Intraoperative Awareness in Awake Craniotomy Patients [PDF]
La craneotomía con paciente despierto (CPD) demanda un manejo multidisciplinario particular debido al componente de conciencia transoperatoria que aporta beneficios en la resección tumoral y preservación neurológica, pero también implica el manejo de los
Esquivel Miranda, Miguel Ángel +5 more
core +1 more source

