Results 51 to 60 of about 232 (61)

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

Acta Neuropathologica, 2012
Pierre Bady, Jocelyne Bloch, Christine Marosi   +2 more
exaly  

Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

Lancet Oncology, The, 2014
Roger Stupp, Monika E Hegi, Jana Portnow
exaly  

Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer

Annals of Oncology, 2015
Pieter Wesseling
exaly  

The prognostic value of MGMT promoter methylation in glioblastoma: A meta‐analysis of clinical trials

Journal of Cellular Physiology, 2018
Maryam Moradi Binabaj, Afsane Bahrami, Seyed Mahdi Hassanian   +2 more
exaly  

A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma

Nature Communications, 2018
Minjie Zhang, Haiyun Gan, Heping Wang
exaly  

O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry

Biochimica Et Biophysica Acta: Reviews on Cancer, 2011
Markus Christmann, Wynand P Roos, Bernd Kaina   +2 more
exaly  

p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents

Oncogene, 1998
Bernd Kaina
exaly  

Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance

Nature Communications, 2015
Malin Wickström, Christer Einvik, Raul Calero   +2 more
exaly  

MGMT: its role in cancer aetiology and cancer therapeutics

Nature Reviews Cancer, 2004
exaly  

MGMT: Key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents

DNA Repair, 2007
Bernd Kaina, Markus Christmann, Wynand P Roos   +2 more
exaly