Results 141 to 150 of about 250,141 (320)

Agronomic Performance of Irrigated and Rainfed Arabica Coffee Cultivars in the Cerrado Mineiro Region

open access: yesAgronomy
Coffee genetic improvement programs have been evolving very quickly, with frequent launches of new cultivars. The adoption of these new genetic materials by rural producers requires knowledge of agronomic performance in different production systems. Thus,
Giovani Belutti Voltolini   +18 more
doaj   +1 more source

Two-Stage Consensus-Based Distributed MPC for Interconnected Microgrids

open access: yes, 2018
In this paper, we propose a model predictive control based two-stage energy management system that aims at increasing the renewable infeed in interconnected microgrids (MGs).
Hans, C. A.   +2 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Centralized multi-microgrid control: peer-to-peer power trading for battery life extension and enhanced outage/fault resilience under generation uncertainty and demand variations

open access: yesInternational Journal of Electrical Power & Energy Systems
This article presents several strategies for managing multi-level peer-to-peer power trading between the microgrids (MGs) within a multi-microgrid (MMG) system and the utility grid.
Hossien Faraji   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Determination of Lipids and Glucose Content in Hydatid Cysts of Echinococcus Granulosus Isolated from Different Intermediate Hosts (Sheep, Goats, Cattle And Human) Tissues

open access: yesScience Journal of University of Zakho, 2013
This study included comparative biochemical composition of hydatid fluid, protoscolices, infected and non-infected tissues isolated from liver and lungs of infected sheep, goats, and cattle slaughtered in Duhok abattoirs during the period from Nov.
Azad A. Meerkhan, Wijdan M.S. Mero
doaj  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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