Major Histocompatibility Complex Class I Matching is Necessary but not Sufficient for Tolerance Induction to Vascularized Composite Allografts After Donor Hematopoietic Cell Transplantation. [PDF]
Manell E +19 more
europepmc +1 more source
The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth +7 more
wiley +1 more source
Retinal Amyloid Clearance Enhanced by 40-Hz Light Flicker via MHC-II+ Microglia Regulation in Mice. [PDF]
Sheng W +8 more
europepmc +1 more source
Cycling water‐in‐salt batteries involves complex degradation processes that require multiprobe analysis. Using online electrochemical mass spectrometry (OEMS), postmortem X‐ray photoemission spectroscopy (XPS) (including hard‐XPS), and scanning electron microscopy (SEM), the degradation mechanisms are examined in composite electrodes (TiS2 and LiFePO4)
Célia Doublet +7 more
wiley +1 more source
Single-cell RNA sequencing unveils CCDC86-driven immune modulation and antigen-presenting cell dynamics in head and neck squamous cell carcinoma. [PDF]
Sun X, Zheng B, Teng X, Xue S, Wu Y.
europepmc +1 more source
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Integrative Roles of NK Receptors and γδ TCRs in γδ T Cell-Mediated Cancer Immunity. [PDF]
Oh WJ, Cho H, Dahanayake TK, Kim TJ.
europepmc +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Improving mental health through body-awareness with dynamic interpersonal therapy in patients with persistent somatic symptoms: an explorative cohort study. [PDF]
Rovers J +3 more
europepmc +1 more source

