Results 91 to 100 of about 4,097 (189)

Stereoselective blockade of central [3H]5-hydroxytryptamine binding to multiple sites (5-HT1A, 5-HT1B and 5-HT1C) by mianserin and propranolol

, 1987
The interaction of the enantiomers of mianserin and propranolol with the binding of [3H]5-hydroxytryptamine ([3H]5-HT) to the 5-HT1A, 5-HT1B and 5-HT1C sites, and with the binding of [3H]ketanserin to the 5-HT2 site, has been evaluated in rat brain ...
Martyn D Wood, Beverley S Alexander
core   +1 more source

Comparative study of the effects of mianserin, a tetracyclic antidepressant, and of imipramine on uptake and release of neurotransmitters in synaptosomes

, 1976
The effects of mianserin, a tetracyclic antidepressant, on uptake and release of [3H]noradrena-line (3H-NA), [3H]dopamine (3H-DA), [3H]-5-hydroxytryptamine(3H-5-HT) and [3H]γ-aminobutyric acid (3H-GABA) in synaptosomes from different areas of the rat ...
Francesco Angelini, Alberto Bertollini, Maurizio Raiteri   +2 more
core   +1 more source

Shared genetic architecture between premenstrual disorder symptoms and major psychiatric disorders suggests a role for calcium signaling

European Psychiatry
Background Major psychiatric disorders (MPDs) and premenstrual disorders (PMDs) are often comorbid, with indications of shared genetic architecture. However, the specific genetic variants underlying this comorbidity remain elusive.
Piotr Jaholkowski, Elgeta Hysaj, Nadine Parker, Erik David Wiström, Elise M. Koch, Pravesh Parekh, Susu Qu, Srdjan Djurovic, Olav Bjerkehagen Smeland, Marit Haram, Kevin Sean O’Connell, Donghao Lu, Alexey A. Shadrin, Ole A. Andreassen   +13 more
doaj   +1 more source

Steady state concentrations of the enantiomers of mianserin and desmethylmianserin in poor and in homozygous and heterozygous extensive metabolizers of debrisoquine

, 1998
Steady state concentrations of (S)- and (R)-mianserin and desmethylmianserin were measured in 21 homozygous extensive metabolizers (as determined by genotyping for mutations 3 {[or A] and 4 [or B]), in seven heterozygous extensive ...
C. Lima, P. Baumann, C. Eap, Powell, Kerry, Baumann, Pierre, Macciardi, Fabio, Woggon, Brigitte, K. Powell, F. Macciardi, de Mendonça Lima, Carlos A., Eap, Chin B., B. Woggon   +11 more
core   +1 more source

Prolactin response to tryptophan during mianserin treatment.

, 1988
Unlike tricyclic antidepressants and monoamine oxidase inhibitors, mianserin did not increase prolactin response to the 5-hydroxytryptamine (5-HT) precursor tryptophan in nine patients with major depression.
Cowen, PJ
core  

The association carbamazepine-mianserin in opiate withdrawal: a double blind pilot study versus clonidine.

, 1997
Our clinic has fortuitously developed the therapeutic use of the association of mianserin (maximum daily dose 90 mg) and carbamazepine (maximum daily dose 400 mg) in opiate withdrawal management.
Bondolfi, G., Velardi, A., Bertschy, G., Baettig, D., Baumann, P., Budry, P., Dascal, D., Bryois, C., Martinet, C.   +8 more
core   +1 more source

Psychosomatic Status Indices in Rheumatoid Arthritis under Treatment with Mianserin Hydroclorid [PDF]

, 2008
USMF “Nicolae Testemiţanu”, Catedra Medicină Internă nr.1 FR şi SC, Catedra Psihiatrie şi Narcologie FPM120 patients (females) with confirmed diagnosis of rheumatoid arthritis were examined.
Groppa, Liliana, Pascari-Negrescu, Ala, Rotaru, Larisa, Agachi, Svetlana, Revenco, Mircea, Deseatnicova, Elena   +5 more
core   +1 more source

Mianserin-induced Up-Regulation of Serotonin Receptors on Normal Human Platelets In Vivo

, 1993
he antidepressant, mianserin, is a serotonin receptor (5-HT2) antagonist and produces down-regulation of 5-HT2 and 5-HT1c receptors in the cerebral cortex of rats.
Jarvis, Michael R., Stedman, Terry J., Pond, Susan M, Csernansky, John G., Whiteford, Harvey A.   +4 more
core   +1 more source

Differences in the regulatory adaptation of the 5HT recognition sites labelled by 3H-mianserin or 3H-ketanserin

, 1983
In crude synaptic membranes prepared from rat brain the sites occupied by 3H-spiroperidol that are displaced by microM concentrations of serotonin (5HT) have been termed 5HT2 receptors (Peroutka and Snyder, 1980).
Gandolfi, O, Barbaccia, ML, Costa, E, Costa, E., BARBACCIA, MARIA LUISA, Chuang, DM   +5 more
core   +1 more source

Computational approach to the prediction of blood-brain partitioning of basic drug candidates using mixed micellar liquid chromatography

مجله دانشگاه علوم پزشکی گرگان, 2017
Background and Objective: The blood–brain barrier (BBB) is considered to be the main barrier to drug transport into the central nervous system. In this study, the capability of biopartitioning micellar chromatography (BMC) using the mixed micellar system
S Arshadi
doaj