Results 81 to 90 of about 4,097 (189)

Elucidation of the structural requirements for the bioactivation of mianserin in-vitro

open access: yes, 1993
The aim of this study was to investigate structure-activity relationships among a series of compounds related to the antidepressant drug, mianserin, with respect to their ability to produce cytotoxic metabolites. Human peripheral lymphocytes were used as
P Roberts, B K Park, N R Kitteringham
core   +1 more source

Deciphering the function of octopaminergic signaling on wing polyphenism of the pea aphid Acyrthosiphon pisum

open access: yesFrontiers in Physiology, 2016
Aphids exhibit wing polyphenism (winged or wingless) for adaption to predictable or temporally heterogeneous environmental changes; however, the underlying mechanism is still unclear.
Xing-Xing Wang   +4 more
doaj   +1 more source

The efficiency of a carbamazepine-mianserin combination scheme in opiate detoxification.

open access: yes, 2004
A recent comparative randomized double-blind study has suggested the utility of a carbamazepine/mianserin combination as a treatment for opiate withdrawal.
Krenz, S.   +5 more
core   +1 more source

Different effects of serotonin antagonists on 3H-mianserin and 3H-ketanserin recognition sites

open access: yes, 1985
In minces prepared from the frontal cortex of rats treated with ketanserin (10 mg/kg i.p.) or mianserin (5 mg/kg i.p.) twice daily for 21 days, the Vmax of the adenylate cyclase stimulated by NE (100 microM) is attenuated, suggesting that ketanserin and ...
Gandolfi, O   +2 more
core   +1 more source

Changes in sleep EEG architecture during the treatment of depressed patients with mianserin

open access: yes, 1985
The effect of mianserin on sleep variables was studied in a single-blind non-controlled trial. Ten depressed hospital in-patients received placebo for one week and then mianserin 60 mg at night for four weeks.
Mendlewicz, Julien   +2 more
core   +1 more source

Interaction between mianserin and acenocoumarin: a single case study.

open access: yes, 1994
A 62-year-old male patient, suffering from a hypertensive cardiopathy, an arteriopathy of the lower extremities and a type II insulin independent diabetes had a prothrombin time ratio R of 2.15 (therapeutic range: 2.1-1.45) during a daily treatment of 4 ...
Baettig, D.   +2 more
core   +1 more source

Dm5-HT2B: Pharmacological Characterization of the Fifth Serotonin Receptor Subtype of Drosophila melanogaster

open access: yesFrontiers in Systems Neuroscience, 2017
Serotonin (5-hydroxytryptamine, 5-HT) is an important regulator of physiological and behavioral processes in both protostomes (e.g., insects) and deuterostomes (e.g., mammals).
Wolfgang Blenau   +4 more
doaj   +1 more source

Concomitant medication, comorbidity and survival in patients with breast cancer

open access: yesNature Communications
Between 30% and 70% of patients with breast cancer have pre-existing chronic conditions, and more than half are on long-term non-cancer medication at the time of diagnosis.
Elise Dumas   +23 more
doaj   +1 more source

Comparison of iprindole, imipramine and mianserin action on brain serotonergic and beta adrenergic receptors

open access: yes, 1984
Iprindole in vitro displaces mianserin from specific recognition sites (IC50 3 microM). Daily doses (5 mg/kg i.p.) of iprindole repeated for 3 weeks attenuate the norepinephrine stimulation of adenylate cyclase studied in brain slices.
Gandolfi, O   +4 more
core   +1 more source

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