Results 81 to 90 of about 4,097 (189)
Elucidation of the structural requirements for the bioactivation of mianserin in-vitro
The aim of this study was to investigate structure-activity relationships among a series of compounds related to the antidepressant drug, mianserin, with respect to their ability to produce cytotoxic metabolites. Human peripheral lymphocytes were used as
P Roberts, B K Park, N R Kitteringham
core +1 more source
Aphids exhibit wing polyphenism (winged or wingless) for adaption to predictable or temporally heterogeneous environmental changes; however, the underlying mechanism is still unclear.
Xing-Xing Wang +4 more
doaj +1 more source
The efficiency of a carbamazepine-mianserin combination scheme in opiate detoxification.
A recent comparative randomized double-blind study has suggested the utility of a carbamazepine/mianserin combination as a treatment for opiate withdrawal.
Krenz, S. +5 more
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Different effects of serotonin antagonists on 3H-mianserin and 3H-ketanserin recognition sites
In minces prepared from the frontal cortex of rats treated with ketanserin (10 mg/kg i.p.) or mianserin (5 mg/kg i.p.) twice daily for 21 days, the Vmax of the adenylate cyclase stimulated by NE (100 microM) is attenuated, suggesting that ketanserin and ...
Gandolfi, O +2 more
core +1 more source
Changes in sleep EEG architecture during the treatment of depressed patients with mianserin
The effect of mianserin on sleep variables was studied in a single-blind non-controlled trial. Ten depressed hospital in-patients received placebo for one week and then mianserin 60 mg at night for four weeks.
Mendlewicz, Julien +2 more
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Interaction between mianserin and acenocoumarin: a single case study.
A 62-year-old male patient, suffering from a hypertensive cardiopathy, an arteriopathy of the lower extremities and a type II insulin independent diabetes had a prothrombin time ratio R of 2.15 (therapeutic range: 2.1-1.45) during a daily treatment of 4 ...
Baettig, D. +2 more
core +1 more source
Serotonin (5-hydroxytryptamine, 5-HT) is an important regulator of physiological and behavioral processes in both protostomes (e.g., insects) and deuterostomes (e.g., mammals).
Wolfgang Blenau +4 more
doaj +1 more source
Concomitant medication, comorbidity and survival in patients with breast cancer
Between 30% and 70% of patients with breast cancer have pre-existing chronic conditions, and more than half are on long-term non-cancer medication at the time of diagnosis.
Elise Dumas +23 more
doaj +1 more source
Iprindole in vitro displaces mianserin from specific recognition sites (IC50 3 microM). Daily doses (5 mg/kg i.p.) of iprindole repeated for 3 weeks attenuate the norepinephrine stimulation of adenylate cyclase studied in brain slices.
Gandolfi, O +4 more
core +1 more source

