Results 61 to 70 of about 6,114 (196)

Antidepressants Use Among Pregnant Women in Denmark From 2001 to 2023: A Population‐Level Drug Utilization Study

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT We evaluated trends in antidepressant use among pregnant women in Denmark from 2001 to 2023, comparing them with a matched comparison group from the general population. Data from the Danish Health Data Authority were used to assess annual antidepressant prescription redemption rates per 1000 pregnancies, with a focus on total antidepressant ...
Anne‐Johanne Andersen, Kasper Nørlund Enevoldsen, Anne Sophie Enevoldsen, Erika B. Gram, Per Damkier   +4 more
wiley   +1 more source

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

Neurogastroenterology &Motility, Volume 37, Issue 10, October 2025.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, Volume 17, Issue 9, Page 1502-1515, September 2025.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

National Prescribing Trends and Cost Analysis of Antidepressants, Anxiolytics, and Hypnotics in England, 2010–2023

Human Psychopharmacology: Clinical and Experimental, Volume 40, Issue 5, September 2025.
ABSTRACT Introduction We describe prescribing of anxiolytics/hypnotics/antidepressants at an all‐England level between 2010 and 2023, taking account of the influence of the COVID‐19 pandemic‐period. Methods All Primary Care Prescribing data for England for anxiolytics/hypnotics/antidepressant agents taken as tablets or capsules from 1 January 2010 to ...
Mike Stedman, Mark Davies, John Warner‐ Levy, Joseph Ingram, David Taylor, Adrian Heald   +5 more
wiley   +1 more source

Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants

Molecular Pain, 2011
Background Fibromyalgia (FM) is characterized by chronic widespread pain, which is often refractory to conventional painkillers. Numerous clinical studies have demonstrated that antidepressants are effective in treating FM pain. We previously established
Mukae Takehiro, Araki Kohei, Nagai Jun, Uchida Hitoshi, Nishiyori Michiko, Kishioka Shiroh, Ueda Hiroshi   +6 more
doaj   +1 more source

Vortioxetine‐induced syndrome of inappropriate secretion of antidiuretic hormone: A case report

Neuropsychopharmacology Reports
Background Vortioxetine, known for its efficacy in treating depression through its effects on various neurotransmitters, has not been previously reported to induce syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
Taro Sasaki, Yunosuke Shindo, Kota Kikuchi, Yasushi Kawamata, Norio Sugawara, Norio Yasui‐Furukori   +5 more
doaj   +1 more source

Deciphering the function of octopaminergic signaling on wing polyphenism of the pea aphid Acyrthosiphon pisum

Frontiers in Physiology, 2016
Aphids exhibit wing polyphenism (winged or wingless) for adaption to predictable or temporally heterogeneous environmental changes; however, the underlying mechanism is still unclear.
Xing-Xing Wang, Yi Zhang, Zhan-Feng Zhang, Hong-gang Tian, Tong-Xian Liu   +4 more
doaj   +1 more source

Dm5-HT2B: Pharmacological Characterization of the Fifth Serotonin Receptor Subtype of Drosophila melanogaster

Frontiers in Systems Neuroscience, 2017
Serotonin (5-hydroxytryptamine, 5-HT) is an important regulator of physiological and behavioral processes in both protostomes (e.g., insects) and deuterostomes (e.g., mammals).
Wolfgang Blenau, Stöppler Daniel, Sabine Balfanz, Markus Thamm, Arnd Baumann   +4 more
doaj   +1 more source

Ameliorating calcium homeostasis improves longevity and healthspan in progeroid and naturally aged mice

Nature Communications
Cellular calcium (Ca2+)-regulating systems are compromised during aging-related disorders. Here, we show that disruption of Ca2+ homeostasis leads to the cytoplasmic accumulation of Ca2+ binding protein S100A6, which promotes Hutchinson-Gilford progeria ...
Weifang Xiang, Qianying Hu, Pingli Sun, Xiaohan Wu, Hui Jiang, Min Qu, Lei Li, Yu Wang, Zhiyao Wang, Xuan Liu, Jun Ma, Dahai Zhu, Hu Li, Yuanyi Wang, Yang Jiao, Baiqu Huang, Jun Lu, Xianling Cong, Wei Li, Yu Zhang   +19 more
doaj   +1 more source

Concomitant medication, comorbidity and survival in patients with breast cancer

Nature Communications
Between 30% and 70% of patients with breast cancer have pre-existing chronic conditions, and more than half are on long-term non-cancer medication at the time of diagnosis.
Elise Dumas, Beatriz Grandal Rejo, Paul Gougis, Sophie Houzard, Judith Abécassis, Floriane Jochum, Benjamin Marande, Annabelle Ballesta, Elaine Del Nery, Thierry Dubois, Samar Alsafadi, Bernard Asselain, Aurélien Latouche, Marc Espie, Enora Laas, Florence Coussy, Clémentine Bouchez, Jean-Yves Pierga, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Judicaël Hotton, Chloé-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy   +23 more
doaj   +1 more source