Results 51 to 60 of about 6,114 (196)

Carbon Nanohorn Suprastructures on a Paper Support as a Sorptive Phase

open access: yesMolecules, 2018
This article describes a method for the modification of paper with single-wall carbon nanohorns (SWCNHs) to form stable suprastructures. The SWCNHs form stable dahlia-like aggregates in solution that are then self-assembled into superior structures if ...
Julia Ríos-Gómez   +4 more
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Psychotropic Drugs for the Management of Chronic Pain and Itch

open access: yesPharmaceuticals, 2019
Clinical observations have shown that patients with chronic neuropathic pain or itch exhibit symptoms of increased anxiety, depression and cognitive impairment. Such patients need corrective therapy with antidepressants, antipsychotics or anticonvulsants.
Daria A. Belinskaia   +4 more
doaj   +1 more source

Function and distribution of 5-HT2 receptors in the honeybee (Apis mellifera). [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Serotonin plays a pivotal role in regulating and modulating physiological and behavioral processes in both vertebrates and invertebrates. In the honeybee (Apis mellifera), serotonin has been implicated in division of labor, visual processing,
Markus Thamm   +6 more
doaj   +1 more source

Delphi Consensus Among French Obesity Experts on Clinical Recommendations for Drug Prescription in Patients With Severe Obesity

open access: yesObesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Introduction Although the physiologic alterations seen in obesity often affect the pharmacokinetics and pharmacodynamics of drugs, most clinical trials do not consider these aspects specifically for this population. To date, there is no list of potentially inappropriate medications for patients living with obesity. The aim of this study was to
Sarah Berdot   +17 more
wiley   +1 more source

Long‐Term Use of Benzodiazepines and Related Drugs in Persons With Major Depressive Disorder

open access: yesBrain and Behavior, Volume 15, Issue 11, November 2025.
ABSTRACT Introduction Benzodiazepines and related drugs (BZDRs) may be prescribed to treat anxiety and insomnia in persons with depression. Although BZDRs are recommended for short‐term use only, their use may be prolonged. Despite research on the use of BZDRs in depression, to our knowledge, long‐term use and its predictors have not been previously ...
Heli Laitinen   +6 more
wiley   +1 more source

Evaluation of Methods Adjusting for Unmeasured Confounding Using Large Healthcare Databases: An Empirical Study Concerning Drugs Inducing Prematurity

open access: yesClinical and Translational Science, Volume 18, Issue 11, November 2025.
ABSTRACT With the growing availability of large healthcare databases for clinical science, mitigating unmeasured confounding has emerged as a major issue in pharmacoepidemiologic studies. Extensions of causal inference methods to high‐dimensional settings could help address this problem, but studies comparing their performance in real‐world databases ...
Chi‐Hong Duong   +7 more
wiley   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González   +8 more
wiley   +1 more source

Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

open access: yeseLife, 2015
Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that ...
Sunitha Rangaraju   +8 more
doaj   +1 more source

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen   +3 more
wiley   +1 more source

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