Results 51 to 60 of about 2,998 (132)

Application of Bar Adsorptive Microextraction for the Determination of Levels of Tricyclic Antidepressants in Urine Samples

Molecules, 2021
This work entailed the development, optimization, validation, and application of a novel analytical approach, using the bar adsorptive microextraction technique (BAμE), for the determination of the six most common tricyclic antidepressants (TCAs ...
Mariana N. Oliveira, Oriana C. Gonçalves, Samir M. Ahmad, Jaderson K. Schneider, Laiza C. Krause, Nuno R. Neng, Elina B. Caramão, José M. F. Nogueira   +7 more
doaj   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González, Yahira Guzman, Nadia Juliana Proaños, Rosa‐Helena Bustos, María Aconcha, Ivan Guerrero, Laura Alejandra Martinez, Michael Berk, Seetal Dodd   +8 more
wiley   +1 more source

Pseudoporphyria secondary to renal failure

Przegląd Dermatologiczny, 2017
Introduction . Pseudoporphyria is a rare disease associated with chronic renal failure. Symptoms of pseudoporphyria may develop in response to UV exposure and medications.
Lilianna Kulczycka-Siennicka, Anna Woźniacka, Remigiusz Szumiński, Agnieszka Żebrowska   +3 more
doaj   +1 more source

Carbon Nanohorn Suprastructures on a Paper Support as a Sorptive Phase

Molecules, 2018
This article describes a method for the modification of paper with single-wall carbon nanohorns (SWCNHs) to form stable suprastructures. The SWCNHs form stable dahlia-like aggregates in solution that are then self-assembled into superior structures if ...
Julia Ríos-Gómez, Beatriz Fresco-Cala, María Teresa García-Valverde, Rafael Lucena, Soledad Cárdenas   +4 more
doaj   +1 more source

Function and distribution of 5-HT2 receptors in the honeybee (Apis mellifera). [PDF]

PLoS ONE, 2013
BACKGROUND: Serotonin plays a pivotal role in regulating and modulating physiological and behavioral processes in both vertebrates and invertebrates. In the honeybee (Apis mellifera), serotonin has been implicated in division of labor, visual processing,
Markus Thamm, Daniel Rolke, Nadine Jordan, Sabine Balfanz, Christian Schiffer, Arnd Baumann, Wolfgang Blenau   +6 more
doaj   +1 more source

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 4, October 2025.
ABSTRACT This scoping review investigates the association between ABCB1 polymorphisms and antidepressant efficacy in humans. A systematic search identified 630 records, of which 58 met the inclusion criteria, resulting in 42 unique studies (five randomised controlled trials (RCTs), two randomised studies (non‐RCTs), 30 prospective cohort studies, three
Sofie Voss Thorsen, Cille Bülow, Kim Dalhoff, David Peick Sonne   +3 more
wiley   +1 more source

Psychotropic Drugs for the Management of Chronic Pain and Itch

Pharmaceuticals, 2019
Clinical observations have shown that patients with chronic neuropathic pain or itch exhibit symptoms of increased anxiety, depression and cognitive impairment. Such patients need corrective therapy with antidepressants, antipsychotics or anticonvulsants.
Daria A. Belinskaia, Mariia A. Belinskaia, Oleg I. Barygin, Nina P. Vanchakova, Natalia N. Shestakova   +4 more
doaj   +1 more source

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

Neurogastroenterology &Motility, Volume 37, Issue 10, October 2025.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, Volume 17, Issue 9, Page 1502-1515, September 2025.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

eLife, 2015
Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that ...
Sunitha Rangaraju, Gregory M Solis, Ryan C Thompson, Rafael L Gomez-Amaro, Leo Kurian, Sandra E Encalada, Alexander B Niculescu III, Daniel R Salomon, Michael Petrascheck   +8 more
doaj   +1 more source