Results 1 to 10 of about 18,661 (239)

Cardiac 123I-MIBG Scintigraphy in Neurodegenerative Parkinson Syndromes: Performance and Pitfalls in Clinical Practice [PDF]

Frontiers in Neurology, 2019
Purpose: Cardiac [123I]metaiodobenzylguanidine scintigraphy (123I-MIBG), reflecting postganglionic cardiac autonomic denervation, is proposed for early detection of Parkinson's disease (PD; reduced tracer uptake) and separation from Multiple System ...
Cornelia Skowronek, Cornelia Skowronek, Leonora Zange, Leonora Zange, Axel Lipp, Axel Lipp   +5 more
doaj   +5 more sources

123I-Methyljodbenzylguanidin- (MIBG-) Szintigraphie [PDF]

Der Pathologe, 2007
Zusammenfassung: Das mit Radiojod markierte Katecholaminanalogon Methyljodbenzylguanidin (MIBG) eignet sich aufgrund seiner selektiven Aufnahme in chromaffine Gewebe in hervorragender Weise für die bildgebende Diagnostik des Phäochromozytoms und besitzt hier nach Literaturangaben eine Sensitivität von etwa 90% und eine Spezifität von annähernd 100 ...
Padberg, B-C, Rordorf, T, Suter, S L, Pfeiffer, D, Wild, D, Schröder, S   +5 more
  +6 more sources

Experimental study on the treatment of norepinephrine transporter-overexpressing pheochromocytomas and paragangliomas: a synthetic lethality strategy combining 131I-MIBG with PARP inhibitors [PDF]

Frontiers in Oncology
IntroductionPheochromocytomas and paragangliomas (PPGLs) are associated with poor prognosis especially in patients with metastatic spread. This study aims to investigate the therapeutic potential of 131I-MIBG and the PARP inhibitor fluzoparib ...
Jieping Song, Lulu Zhang, Fan Qiu, Xiumin Shi, Rui Tian, Chuan Zhang, Xiaoyuan Li, Feng Wang   +7 more
doaj   +2 more sources

A case of adrenal endothelial cyst (vascular type) with positive 123I-MIBG uptake [PDF]

Urology Case Reports
123I-metaiodobenzylguanidine (MIBG) scintigraphy is highly accurate for diagnosing pheochromocytoma and paraganglioma (PPGL), and positive uptake in non-PPGL adrenal lesions is rare.
Riona Asai, Tomonori Sato, Yuto Yamazaki, Yuta Tezuka, Yoshikiyo Ono, Hiromichi Katayama, Yohei Satake, Takuma Sato, Yoshihide Kawasaki, Naoki Kawamorita, Hideki Katagiri, Akihiro Ito   +11 more
doaj   +2 more sources

Evaluating the diagnostic efficacy of whole-body MRI versus 123I-mIBG/131I-mIBG imaging in metastatic pheochromocytoma and paraganglioma [PDF]

Scientific Reports
This study aimed to compare tumor lesion detectability and diagnostic accuracy of whole-body magnetic resonance imaging (WB-MRI) and radioiodine-labeled meta-iodo-benzylguanidine (mIBG) imaging techniques in patients with metastatic pheochromocytoma and ...
Hiroshi Mori, Hiroshi Wakabayashi, Shintaro Saito, Kenichi Nakajima, Kotaro Yoshida, Tomo Hiromasa, Seigo Kinuya   +6 more
doaj   +2 more sources

[¹²³I]-mIBG and [¹⁸F]-FDOPA differential uptake in the follow-up of neonatal neuroblastoma. [PDF]

EJNMMI Rep
Edet-Sanson A, Lechevallier M, Modzelewski R, Becker S, Bouyeure-Petit AC, Bohn P.   +5 more
europepmc   +3 more sources

Crisis after angiography: time for MIBG [PDF]

The Lancet, 1998
D C, Costa, J B, Bomanji
openaire   +3 more sources

Metastatic Pheochromocytoma Diagnosed with 131I-MIBG SPECT/CT Imaging in a Patient with Pathogenic VHL Mutation

World Journal of Nuclear Medicine, 2022
Pheochromocytoma is a rare catecholamine secreting neuroendocrine tumor arising from chromaffin cells of adrenal medulla with approximate prevalence of 0.1 to 0.6% in patients suffering from hypertension.
Kousik Vankadari, Raman Boddula, Aditya Gajanan Hegde, Chimutai Chinte   +3 more
doaj   +1 more source

Thyroid [123I]MIBG uptake in Parkinson’s disease and diabetes mellitus

IBRO Neuroscience Reports, 2023
Thyroid [123I]MIBG uptake is proposed as a tool for differentiating between Parkinson’s disease (PD) and diabetes mellitus (DM) on [123I]MIBG scintigraphies since both patient groups show decreased cardiac uptake.
Tatyana D. Fedorova, Karoline Knudsen, Thorsten K. Rasmussen, Jacob Horsager, Adjmal Nahimi, Casper Skjærbæk, Eva Schaeffer, Daniela Berg, Astrid J. Terkelsen, Per Borghammer   +9 more
doaj   +1 more source

Establishment of Quality Standard for Metaiodobenzylguanidine as Radiopharmaceutical Precursor

Journal of Isotopes, 2023
Meta-iodobenzylguanidine (MIBG) is used as a chemical precursor of radioiodinated (123I or 131I) MIBG preparation. In order to control the quality of MIBG, in this study, Infrared identification of self-made MIBG was carried out, the physical and ...
CHEN Mengyi;DONG Ruilin;XING Yu;ZHOU Jiajun;QIU Shanshan;SUN Mingyue;WANG Xiaoming;WU Fuhai;HU Ji
doaj   +1 more source