Results 181 to 190 of about 14,868 (228)

Quantitative I-123 mIBG SPECT in differentiating abnormal and normal mIBG myocardial uptake

Journal of Nuclear Cardiology, 2012
The purpose of this study was to evaluate global quantitation of cardiac uptake on I-123 mIBG SPECT.The study included a pilot group of 67 subjects and a validation group of 1,051 subjects. SPECT images were reconstructed by filtered backprojection, ordered subsets expectation maximization, and deconvolution of septal penetration, respectively.
Ji, Chen, Russell D, Folks, Liudmila, Verdes, Daya N, Manatunga, Arnold F, Jacobson, Ernest V, Garcia   +5 more
openaire   +2 more sources

Radiochemistry, biochemistry, and kinetics of ¹³¹I‐metaiodobenzylguanidine (MIBG) and ¹²³I‐MIBG: Clinical implications of the use of ¹²³I‐MIBG

Medical and Pediatric Oncology, 1987
AbstractMetaiodobenzylguanidine (MIBG) is actively concentrated in adrenergic neuroendocrine tissues and tumors by an active, energyand sodium‐dependent, high‐affinity, saturable mechanism. This has proved successful, when labeled with 131‐l or 123‐l, in scintigraphically depicting pheochromocytomas and neuroblastomas.For imaging purposes 123‐l has ...
B, Shapiro, M D, Gross
openaire   +2 more sources

Guidelines for radioiodinated MIBG scintigraphy in children

European Journal of Nuclear Medicine and Molecular Imaging, 2003
These guidelines on the use of radioiodinated (99m)Tc-MIBG scintigraphy in children, which summarise the views of the Paediatric Committee of the European Association of Nuclear Medicine, provide a framework which may prove helpful to nuclear medicine teams in daily practice. They have been influenced by the conclusions of the "Consensus Guidelines for
Oliver, P., Colarinha, P., Fettich, J., Fischer, S., Frøkiær, Jørgen, Gimmarile, F., Gordon, I., Hahn, K., Kabasakal, L., Mann, M., Mitjavila, M., Piepz, A., Porn, U., Sixt, R., van Velzen, J.   +14 more
openaire   +5 more sources

Positive MIBG scanning at the time of relapse in neuroblastoma which was MIBG negative at diagnosis.

The British Journal of Radiology, 1997
Metaiodobenzylguanidine (MIBG) labelled with iodine-123 (123I) or 131I has become a well established tool with high sensitivity and specificity in the diagnosis and staging of neuroblastoma in children. However, some neuroblastomas do not take up MIBG at the time of diagnosis.
K B, Schwarz, I, Driver, I J, Lewis, R E, Taylor   +3 more
openaire   +2 more sources

131I-MIBG Therapy

2012
Metaiodobenzylguanidine (MIBG) is an analog of guanethidine which has been used for imaging a variety of neuroendocrine tumors (NETs). While 131I-MIBG is approved by the FDA for imaging, no reagents are yet approved for therapy. Thus, 131I-MIBG used for therapy trials is either made in accordance with USP regulations or used under an investigational ...
Jorge A. Carrasquillo, Clara C. Chen
openaire   +1 more source

Metastatic Pulmonary Pheochromocytomas: Positive I-123 MIBG SPECT With Negative I-131 MIBG and Equivocal I-123 MIBG Planar Imaging

CLINICAL NUCLEAR MEDICINE, 1997
Pulmonary metastases from malignant pheochromocytoma were seen with I-123 MIBG SPECT in a 16-year-old girl but were not visualized with I-123 MIBG planar imaging. She had a left adrenalectomy for a pheochromocytoma 7 years earlier. Two small pulmonary nodules were seen on chest X-ray and CT scans.
S, Tsuchimochi, M, Nakajo, Y, Nakabeppu, A, Tani   +3 more
openaire   +2 more sources

Techniques for Imaging with mIBG

1989
Imaging with mIBG has the advantage that the abnormality is seen as an area of increased radioactivity in a background of less activity, facilitating detection and interpretation. The mIBG images have been shown, by many centres, to demonstrate lesions not visible on other modalities; therefore mIBG scintigraphy is now accepted by most paediatric ...
Judy S. E. Moyes, V. Ralph McCready, Ann C. Fullbrook   +2 more
openaire   +1 more source

Procedure guidelines for MIBG-scintigraphy in children

Nuklearmedizin, 2008
SummaryThe German translation of the EANM guideline for MIBG scintigraphy in children (Olivier P et al. EJNM MI 2003; 30: B45–B50; Hahn K. Der Nuklearmediziner 2002; 25: 101–105) was reviewed and actualized according to current publications, legal requirements and conditions in Germany.
C, Franzius, M, Schmidt, B, Hero, T, Pfluger, K, Hahn   +4 more
openaire   +2 more sources

MIBG and risk stratification

Heart, 2011
To the Editor I would like to mention the place of iodine-123 metaiodobenzylguanidine (123I MIBG) as another …
openaire   +1 more source

The Importance of Renal Localization with MIBG Scintigraphy

Clinical Nuclear Medicine, 2002
Although I-123 metaiodobenzylguanidine (MIBG) imaging is a well-validated technique for identification and evaluation of a pheochromocytoma, accurate interpretation can be confounded by tracer retention within the renal pelvis. The authors report two cases of abnormal MIBG accumulation in which renal localization was essential. In the first case, renal
Yang-Yi, Ong, Deborah, Cohn, Johan, Wijaya, Paul, Roach   +3 more
openaire   +2 more sources