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Technical Considerations for MIBG Cardiac Scintigraphy
2016The most commonly used means of imaging to assess cardiac sympathetic denervation is cardiac 123I-metaiodobenzylguanidine (123I-MIBG) scintigraphy. The heart-to-mediastinum (H/M) ratio generated by planar imaging is used widely to assess sympathetic nerve involvement.
Hirohisa Watanabe, Gen Sobue
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I-123-MIBG scintigraphy in patients with neuroblastoma
Nuklearmedizin, 2018SummaryAim: According to German guidelines, I-123-MIBG scintigraphy in neuroblastoma (NB) is preferably performed as early (about 4 h p.i.) and late (24 h p.i.) planar imaging and single- photon emission computed tomography (SPECT) or SPECT/CT 24 h p.i.
Imke Schatka +5 more
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Use of 131I-MIBG Scintigraphy in the Evaluation of Suspected Pheochromocytoma
Mayo Clinic Proceedings, 1985Studies at the University of Michigan have shown that 131I-metaiodobenzylguanidine (131I-MIBG) is an effective agent for the diagnosis and localization of pheochromocytomas and paragangliomas. We conducted a study that confirmed and expanded that finding.
S J, Swensen +6 more
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An Introduction to MIBG Cardiac Scintigraphy
2016Meta-iodobenzylguanidine (MIBG), a guanethidine analog, has an uptake and storage mechanism similar to that of noradrenaline. Using this agent, we can noninvasively assess the pathophysiology of postganglionic cardiac sympathetic nerve endings. Cardiac scintigraphy using MIBG radiolabeled with iodine-123 (123I-MIBG) has been applied to patients with ...
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Cardiac MIBG scintigraphy in Primary Progressive Freezing Gait
Parkinsonism & Related Disorders, 2009Freezing of gait (FOG) generally occurs as a late manifestation of Parkinson's Disease (PD). FOG, however, can present in isolation, constituting the so-called "Primary Progressive Freezing Gait"(PPFG). Myocardial (123)Metaiodiobenzylguanidine (MIBG) enables the assessment of postganglionic sympathetic cardiac nerve terminals.
Salsone M +13 more
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MIBG Scintigraphy in Parkinsonian Syndromes
2002Active uptake of [123I] metaiodobenzylguanidine (MIBG) reflects localisation and functional integrity of postganglionic adrenergic neurons. There is accumulating evidence, that in patients with Parkinson’s disease MIBG uptake into cardiac sympathetic neurons is selectively and grossly reduced.
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[I-MIBG scintigraphy in the diagnosis of neuroblastoma in children].
Journal belge de radiologie, 1990Since the early eighties, *I-MIBG (= *I-metaiodobenzylguanidine), which is stored in the neurotransmitter storage granules of chromaffin cells, has been increasingly used for the detection of pheochromocytomas and allied sympathoadrenal pathologies. The aim of this paper is to illustrate, by means of clinical examples, the role of *I-MIBG-scintigraphy ...
Jacobs, A. +7 more
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123I-MIBG myocardial scintigraphy in diabetic patients
Nuclear Medicine Communications, 1996The aim of this study was to investigate the relationship between autonomic nerve dysfunction and myocardial uptake of 123I-meta-iodobenzyl guanidine (MIBG) in patients with diabetes mellitus. Twenty-two non-insulin-dependent diabetic patients, 9 with autonomic neuropathy [ANP(+)] and 13 without autonomic neuropathy [ANP(-)], and 8 controls were ...
S, Nagamachi +10 more
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[Cardiac sympathetic innervation imaging with myocardial MIBG scintigraphy].
Recenti progressi in medicina, 2013Metaiodobenzylguanidine (MIBG) was developed initially as a tracer for oncological imaging; when labeled with 123 I or 131 I, it may detect APUDomas, such as pheochromocytomas and paragangliomas. In the last years, MIBG has found an important role also in neurology and cardiology, as cardiac innervation tracer.
Genovese, Eugenio Annibale +7 more
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[Indications for MIBG scintigraphy in the diagnosis of neuroblastoma].
Nuklearmedizin. Nuclear medicine, 1989The significance and indications of MIBG scintigraphy are critically assessed. The results are compared with the results of whole-body bone scintigraphy, computed tomography (CT) and magnetic resonance tomography (MRT), and are related to values of catecholamine metabolites in 24-h urines.
K A, Hausegger +3 more
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