Results 71 to 80 of about 49,667 (305)

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

open access: yesAdvanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu   +8 more
wiley   +1 more source

Network, Cryptography, and the Next World to Come: An Everlasting American Techno-millenarianism?

open access: yesZygon
To understand the nexus between networked cryptography and American religiosity, it is essential to embed this inquiry within the broader context of religious imaginaries associated with communication networks in nineteenth-century North America and ...
David Pucheu
doaj   +2 more sources

DNA‐Guided Robust Single‐Protein Electronic Readout

open access: yesAdvanced Science, EarlyView.
Electronic measurements of single proteins can reveal fundamental insights into their structure, dynamics, and interactions, but reproducibility is severely limited by the intrinsic structural heterogeneity of proteins combined with uncontrolled molecular orientation and electrode contact geometries.
Ziyi Ju   +3 more
wiley   +1 more source

Évolution des désignations neutres, positives et négatives dans les émissions de libre antenne de la radio Skyrock (2003-2023)

open access: yesActa Universitatis Lodziensis: Folia Litteraria Romanica
Trois émissions de libre antenne de la radio jeune Skyrock, enregistrées en 2003, 2013 et 2023, sont analysées d’un point de vue argotologique pour discuter la circulation des lexèmes désignant des personnes de façon neutre, positive et négative.
Anne-Caroline Fiévet
doaj   +1 more source

Mechanical and tribological behavior of flyash, red mud and mica particles reinforced Al7075 alloy hybrid metal composites [PDF]

open access: gold, 2022
Siddesh Matti   +5 more
openalex   +1 more source

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

open access: yesAdvanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi   +15 more
wiley   +1 more source

Displacive In‐Plane Ferroelectricity with Domain‐Specific Curie Temperature in Van der Waals Semiconductors

open access: yesAdvanced Science, EarlyView.
Temperature‐dependent electron diffraction on tin monochalcogenides demonstrates a gradual displacive transformation between ferroelectric and paraelectric phases with significant variability in lattice constants and Curie temperature (TC). Periodic variations exist even between domains in individual crystals, implying a domain‐specific Curie ...
Peter Sutter, Eli Sutter
wiley   +1 more source

Image-Based Profiling in Live Cells Using Live Cell Painting

open access: yesBio-Protocol
High-content analysis (HCA) is a powerful image-based approach for phenotypic profiling and drug discovery, enabling the extraction of multiparametric data from individual cells.
Thaís Moraes-Lacerda   +3 more
doaj   +1 more source

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