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Low-level sarin-induced alteration of immune system reaction in inbred BALB/c mice

Toxicology, 2003
To study the influence of low-level sarin inhalation exposure on immune functions, inbred BALB/c mice were exposed to low concentrations of sarin for 60 min in the inhalation chamber. Two concentrations of sarin were chosen-asymptomatic concentration (LEVEL 1) and non-convulsive symptomatic concentration (LEVEL 2).
Jirí, Kassa   +5 more
openaire   +2 more sources

Plasmodium yoelii: An inbred model for protective immunization against malaria in BALB/c mice

Experimental Parasitology, 1977
Abstract Two lines of the 17X strain of Plasmodium yoelii (P. berghei y.) were used in a demonstration of protective immunity against murine malaria. Both lines were invariably lethal to normal BALB/c mice. γ-irradiated P . yoelii -infected mouse erythrocytes were used as an experimental immunogen.
R A, Wells   +3 more
openaire   +2 more sources

Comparison of the pathogensis of two isolates of Besnoitia caprae in inbred BALB/c mice

Veterinary Research Communications, 2010
This study was performed to evaluate the infectivity of bradyzoites of two Besnoitia caprae isolates, BC-1 and BC-2, to inbred BALB/c mice. Each group of inbred BALB/c mice was inoculated intraperitoneally with 1 x 10(3), 1 x 10(4), 1 x 10(5), 5 x 10(5) and 1 x 10(6) of one of the two isolates of B. caprae bradyzoites. The mice were monitored daily for
Ahmad, Oryan   +4 more
openaire   +2 more sources

The Alteration of Immune Reactions in Inbred BALB/cMice Following Low-Level Sarin Inhalation Exposure

Inhalation Toxicology, 2004
To study the influence of low-level sarin inhalation exposure on immune functions, inbred BALB/c mice were exposed to low concentrations of sarin for 60 min in the inhalation chamber. The evaluation of immune functions was carried out using phenotyping of CD3 (T lymphocytes), CD4 (helper T lymphocytes), CD8 (cytotoxic T lymphocytes), and CD19 cells (B ...
Jirí, Kassa   +5 more
openaire   +2 more sources

Effects of hippocampal and lateral hypothalamic electrical stimulation on hippocampal cholinergic mechanisms in BALB/c inbred mice

Neuroscience Letters, 1977
Electrical stimulation of the hippocampus (HPC) and of the lateral hypothalamus (LH) were found to have the same 24 h delayed effect on choline acetyltransferase activity. Since previous experiments demonstrated that these treatments had the same effect on memory storage processes, the present finding and earlier neurochemical investigations suggest ...
Destrade, C   +4 more
openaire   +2 more sources

Natural autoantibodies in nude and normal outbred (Swiss) and inbred ( ) mice

Journal of Autoimmunity, 1989
Spleen cells from adult unprimed outbred (Swiss) and inbred (BALB/c) mice, either normal (no) or athymic-nude (nu) as well as spleen cells from Swiss nude mice bearing two different human tumors (BUR and PINQ), were fused with the mouse non-secreting myeloma cell line P3X63 Ag8-653.
P, Lymberi   +3 more
openaire   +2 more sources

Enhancement of cellular immune function during cold adaptation of inbred mice

Cryobiology, 1992
The cell-mediated immune function of cold-adapted BALB/c inbred mice was studied in experiments of splenic lymphocyte blastogenesis, indicated by tritium-labeled deoxythymidine incorporation and SDS-PAGE autoradiography of synthetic proteins in lymphocytes.
Y, Xu, Z, Yang, C, Su
openaire   +2 more sources

Lactoferrin enhances efficacy of the BCG vaccine: comparison between two inbred mice strains (C57BL/6 and BALB/c)

Tuberculosis, 2009
The current vaccine for tuberculosis (TB), an attenuated strain of Mycobacterium bovis Bacillus Calmette Guerin (BCG), is effective to prevent childhood onset of the disease, but its efficacy is reduced in adults. One strategy to improve the existing vaccine is to develop more effective adjuvants.
Shen-An, Hwang   +3 more
openaire   +2 more sources

The Influence of Single or Repeated Low‐Level Sarin Exposure on Immune Functions of Inbred BALB/c Mice

Basic & Clinical Pharmacology & Toxicology, 2004
Abstract: To study the influence of single or repeated low‐level sarin inhalation exposure on immune functions, inbred BALB/c mice were exposed to low clinically asymptomatic concentrations of sarin for 60 min. in the inhalation chamber. The evaluation of immune functions was carried out using phenotyping of CD3 (T‐lymphocytes), CD4 (helper T ...
Jirí, Kassa   +5 more
openaire   +2 more sources

Mast cell‐derived histamine and tumour necrosis factor: Differences between SJL/J and BALB/c inbred strains of mice

Immunology & Cell Biology, 1996
SummaryMast cells cultured from bone marrow of BALB/c and SJL/J inbred strains of mice using IL‐3 showed distinct patterns of growth and marked differences in their content of TNF‐α and histamine. Mast cells derived from SJL/J mice grew and matured at a faster rate than those from BALB/c bone marrow.
B F, Bebo   +3 more
openaire   +2 more sources

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