Change in Recessive Lethal Alleles Frequency in Inbred Populations [PDF]
In a population practicing consanguineous marriage, rare recessive lethal alleles (RRLA) have higher chances of affecting phenotypes. As inbreeding causes more homozygosity and subsequently more deaths, the loss of individuals with RRLA decreases the frequency of these alleles.
arxiv
The pattern and distribution of deleterious mutations in maize [PDF]
Most non-synonymous mutations are thought to be deleterious because of their effect on protein sequence. These polymorphisms are expected to be removed or kept at low frequency by the action of natural selection, and rare deleterious variants have been implicated as a possible explanation for the "missing heritability" seen in many studies of complex ...
arxiv
Fast Computation of the Kinship Coefficients [PDF]
For families, kinship coefficients are quantifications of the amount of genetic sharing between a pair of individuals. These coefficients are critical for understanding the breeding habits and genetic diversity of diploid populations. Historically, computations of the inbreeding coefficient were used to prohibit inbred marriages and prohibit breeding ...
arxiv
Interindividual and interstrain variations in cholesterol absorptionefficiency occur in humans and animals. We investigated physiological biliaryand small intestinal factors that might determine variations in cholesterolabsorption efficiency among inbred
David Q-H. Wang+2 more
doaj
Strain differences between C57Bl/6 and DBA/2 mice (<i>Mus musculus</i>) in delayed matching and nonmatching-to-position tasks: impact of sample responses and delay intervals. [PDF]
Goto K.
europepmc +1 more source
The hypervirulent Type-1/Type-17 phenotype of <i>Cryptococcus neoformans</i> clinical isolates is specific to A/J mice. [PDF]
Ding M+5 more
europepmc +1 more source
Evaluation of intake of aged garlic extract and organosulfur compounds on progressive hearing loss in DBA/2J mice. [PDF]
Oike H+3 more
europepmc +1 more source
Effects of exercise on vascular remodelling and fetal growth in uncomplicated and abortion-prone mouse pregnancies. [PDF]
Lovell EAK+6 more
europepmc +1 more source
Insight into noncanonical small noncoding RNAs in Influenza A virus infection. [PDF]
Ko EA, Zhou T, Ko JH.
europepmc +1 more source