Results 101 to 110 of about 19,573 (206)

Co-Housing Rodents with Different Coat Colours as a Simple, Non-Invasive Means of Individual Identification:Validating Mixed-Strain Housing for C57BL/6 and DBA/2 Mice [PDF]

, 2013
Standard practice typically requires the marking of laboratory mice so that they can be individually identified. However, many of the common methods compromise the welfare of the individuals being marked (as well as requiring time, effort, and/or ...
A Ennaceur, A Santoso, BC Jones, C Touma, C Touma, Carole Fureix, CC Burn, CL Howerton, CM Nevison, CM Nevison, CZ Cannon, DB Sorensen, DC Schaefer, E Choleris, ED Berglund, ES Orwoll, F Dellu, G Griebel, Georgia Mason, GJ Mason, GJ Sanger, H Harizi, IAS Olsson, IHE Kasanen, J Podhorna, J Vaahtovuo, JA Newman, JC Gonder, JL Hurst, JP Curley, JP Garner, JS Han, K Brennan, K Dahlborn, K Priebe, KG Brand, LE Elcock, MD Walker, Michael Walker, MJ Castelhano-Carlos, MK Meijer, P Cinelli, P Singer, P Toivanen, P Willner, PV Guillot, R Adamec, R Palme, R Trullas, R Urban, RMJ Deacon, Rupert Palme, S Cabib, S Iwaki, S Le Calvez, S Pothion, SH Hurlbert, SH Richter, SLC Tilly, SP Kelley, SS Moy, T Tillmann, TC Goes, TS Perlstein, Wim E. Crusio, WJ Sheward, WO Williams, Y Winter   +67 more
core   +3 more sources

Atp1a2 and Kcnj9 Are Candidate Genes Underlying Sensitivity to Oxycodone‐Induced Locomotor Activation and Withdrawal‐Induced Anxiety‐Like Behaviors in C57BL/6 Substrains

Genes, Brain and Behavior, Volume 24, Issue 1, February 2025.
We exploited near‐isogenic C57BL/6 substrains to fine‐map a 2.45‐Mb region containing DNA variants underlying oxycodone behaviors. We mapped a genomic region on distal chromosome 1 and identified genotype‐driven, differentially expressed mRNAs and proteins within this region and DNA variants.
Lisa R. Goldberg, Britahny M. Baskin, Jacob A. Beierle, Yahia Adla, Julia C. Kelliher, Emily J. Yao, Stacey L. Kirkpatrick, Eric R. Reed, David F. Jenkins, Jiayi Cox, Alexander M. Luong, Kimberly P. Luttik, Julia A. Scotellaro, Timothy A. Drescher, Sydney B. Crotts, Neema Yazdani, Martin T. Ferris, W. Evan Johnson, Megan K. Mulligan, Camron D. Bryant   +19 more
wiley   +1 more source

Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds.

PLoS ONE, 2017
Quantitative trait locus (QTL) analyses of intercross populations between widely used mouse inbred strains provide a powerful approach for uncovering genetic factors that influence susceptibility to atherosclerosis.
Natalia Makhanova, Andrew P Morgan, Yukako Kayashima, Andrei Makhanov, Sylvia Hiller, Svetlana Zhilicheva, Longquan Xu, Fernando Pardo-Manuel de Villena, Nobuyo Maeda   +8 more
doaj   +1 more source

Determining the heritability of ethanol-induced locomotor sensitization in mice using short-term behavioral selection [PDF]

, 2013
RATIONALE: Sensitization to the locomotor stimulant effects of alcohol (ethanol) is thought to be a heritable risk factor for the development of alcoholism that reflects progressive increases in the positive motivational effects of this substance ...
Boehm II, Stephen L., Linsenbardt, Linsenbardt, David N.   +2 more
core   +1 more source

Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice

Behavioral and Brain Functions, 2011
Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura, Eisener-Dorman Amy F, Tarantino Lisa M   +2 more
doaj   +1 more source

Vaccination in murine schistosomiasis with adult worm derived antigens - II. Protective and immune response in inbred mice

Memorias do Instituto Oswaldo Cruz, 1992
Previous work in our laboratory, mainly foccused the prospects of achieving resistance against Schistosoma mansoni infection with adult worm-derived antigens in the form of a soluble extract (SE).
Miriam Tendler, Roberto Magalhães Pinto, Antonio de Oliveira Lima, Wilson Savino, Naftale Katz   +4 more
doaj   +1 more source

Genetic background strongly influences the bone phenotype of P2X7 receptor knockout mice [PDF]

, 2012
The purinergic P2X7 receptor is expressed by bone cells and has been shown to be important in both bone formation and bone resorption. In this study we investigated the importance of the genetic background of the mouse strains on which the P2X7 knock-out
Beck Jensen, J. E., Chessell, I., Gartland, A., Jorgensen, N. R., Petersen, S., Schwarz, P., Steinberg, T. H., Syberg, S., Teilmann, J.   +8 more
core   +3 more sources

Genetic factors at the enterocyte level account for variations inintestinal cholesterol absorption efficiency among inbred strains of mice1

Journal of Lipid Research, 2001
Interindividual and interstrain variations in cholesterol absorptionefficiency occur in humans and animals. We investigated physiological biliaryand small intestinal factors that might determine variations in cholesterolabsorption efficiency among inbred
David Q-H. Wang, Beverly Paigen, Martin C. Carey   +2 more
doaj   +1 more source

Antitumor effect of lysine-isopeptides [PDF]

, 2002
Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect.
Almás, M, Gáborjányi, R, Khlafulla, A R, Pál, K, Szende, B, Szökán, Gy, Tyihá, E   +6 more
core   +4 more sources

Very mild disease phenotype of congenic Cftr^{TgH(neoim)Hgu} cystic fibrosis mice

BMC Genetics, 2008
Background A major boost to cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic
Leonhard-Marek Sabine, Burmester Marion, Bot Alice, Charizopoulou Nikoletta, Wedekind Dirk, Jansen Silke, Dorsch Martina, Stanke Frauke, Wilke Martina, Tóth Balázs, de Jonge Hugo R, Hedrich Hans-Jürgen, Breves Gerhard, Tümmler Burkhard   +13 more
doaj   +1 more source