Results 81 to 90 of about 1,160,575 (212)
The TP53 tumor suppressor gene: From molecular biology to clinical investigations
Journal of Internal Medicine, Volume 298, Issue 2, Page 78-96, August 2025.Abstract Extensively studied over the past four decades, the TP53 gene has emerged as a pivotal watchman in cellular defense and a key factor in cancer biology. TP53 is the most frequently mutated gene in human malignancies, 50% of which carry alterations to it.
Panagiotis Baliakas, Thierry Soussi
wiley +1 more source
Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity-0
, 2011 Copyright information:Taken from "Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity"BMC Neuroscience 2005;6():18-18.Published online 17 Mar 2005PMCID:PMC1079866.Copyright © 2005 Airey et al; licensee BioMed ...
Katherine M Enzinger (71411) +4 more
core +1 more source
Low rate of NADPH/ADP-iron dependent lipid peroxidation in hepatic microsomes of DBA/2 mice [PDF]
, 1985 Hepatic microsomal lipid peroxidation has been studied in 4 inbred strains of mice: C57BL/6, BALB/c, AKR and DBA/2. The rates of lipid peroxidation stimulated in vitro by carbon tetrachloride, ascorbate-iron and cumene hydroperoxide were similar in all 4
Cheeseman, Kevin H. +11 more
core +1 more source
Does tolerance to ethanol-induced ataxia explain the sensitized response to ethanol?
Frontiers in PsychiatryUnder conditions of repeated exposure to ethanol, a sensitized locomotor stimulant response develops in some strains of mice. It has been hypothesized that the sensitized response is a consequence of tolerance development to the sedative/incoordinating ...
Cheryl Reed +4 more
doaj +1 more source
MYH6‐Cre Insertion Accelerates Cardiac Phenotype in Dystrophic D2‐mdx Mice
The FASEB Journal, Volume 39, Issue 14, 31 July 2025.D2.B10‐Dmdmdx/J dystrophic mice were crossed with Tg(myh6‐cre)1Jmk/J mice to create a cardiac‐specific Myh6‐cre (Cre+) promoter region on the D2‐mdx background. Cre+ dystrophic animals demonstrate worse right and left ventricular systolic function, which correlates with increased cardiac‐specific fibrosis and ultimately reduced survival.
India K. Hawkins +6 more
wiley +1 more source
PLoS ONE, 2017 Quantitative trait locus (QTL) analyses of intercross populations between widely used mouse inbred strains provide a powerful approach for uncovering genetic factors that influence susceptibility to atherosclerosis.
Natalia Makhanova +8 more
doaj +1 more source
Cocaine locomotor activation, sensitization and place preference in six inbred strains of mice
Behavioral and Brain Functions, 2011 Background The expanding set of genomics tools available for inbred mouse strains has renewed interest in phenotyping larger sets of strains. The present study aims to explore phenotypic variability among six commonly-used inbred mouse strains to both ...
Grabowski-Boase Laura +2 more
doaj +1 more source
Genetic dissection of susceptibility to audiogenic seizures in inbred mice.
, 1991 Mice of some inbred strains, such as 21-day-old DBA/2J mice, have generalized convulsions when exposed to intense auditory stimulation. Analysis of susceptibility to audiogenic seizures in BXD recombinant inbred strains has demonstrated the influence ...
Neumann, P E, Collins, R L
core +1 more source
Memorias do Instituto Oswaldo Cruz, 1992 Previous work in our laboratory, mainly foccused the prospects of achieving resistance against Schistosoma mansoni infection with adult worm-derived antigens in the form of a soluble extract (SE).
Miriam Tendler +4 more
doaj +1 more source
Journal of Lipid Research, 2001 Interindividual and interstrain variations in cholesterol absorptionefficiency occur in humans and animals. We investigated physiological biliaryand small intestinal factors that might determine variations in cholesterolabsorption efficiency among inbred
David Q-H. Wang +2 more
doaj +1 more source