Results 71 to 80 of about 1,160,575 (212)

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source

Reward-related behavioral paradigms for addiction research in the mouse: performance of common inbred strains. [PDF]

PLoS ONE, 2011
The mouse has emerged as a uniquely valuable species for studying the molecular and genetic basis of complex behaviors and modeling neuropsychiatric disease states.
Lauren Lederle, Susanna Weber, Tara Wright, Michael Feyder, Jonathan L Brigman, Hans S Crombag, Lisa M Saksida, Timothy J Bussey, Andrew Holmes   +8 more
doaj   +1 more source

Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose‐mediated peritoneal injury in mice

Physiological Reports, Volume 13, Issue 22, November 2025.
High‐glucose peritoneal dialysis (PD) fluid induces oxidative stress, inflammation, and fibrosis in the peritoneum. In vivo, Nnt‐deficient C57BL/6J mice showed significantly reduced PD‐induced peritoneal injury, inflammation, and fibrosis compared with Nnt‐competent C57BL/6N controls.
Margarete C. Ohse, Song Rong, Sonja Schmidt, Michael S. Balzer, Christoph Nikolin, Sibylle von Vietinghoff, Hermann Haller, Kai M. Schmidt‐Ott, Yulia Kiyan, Nelli Shushakova   +9 more
wiley   +1 more source

Enhancing sudden unexpected death in epilepsy (SUDEP) research through development of common data elements

Epilepsia Open, Volume 10, Issue 5, Page 1426-1438, October 2025.
Abstract Objective Sudden Unexpected Death in Epilepsy (SUDEP) is a fatal complication for individuals living with epilepsy and is associated with significant personal and public burden. While certain neurotransmitters and neuronal pathways have been associated with SUDEP, the exact biological mechanisms are unknown.
Sloka S. Iyengar, Elaine K. O'Loughlin, Lauren Harte‐Hargrove, Mary Holmay, Laura S. Lubbers, CURE Epilepsy SUDEP Data Standardization Project Steering Committee, CURE Epilepsy SUDEP Data Standardization Project Working Group Members, Lisa M. Bateman, Edward Glasscock, Samden Lhatoo, Philippe Ryvlin, Kristina Simeone, Charles Akos Szabo, Melanie Whittamore‐Mantzios, David Auerbach, Gordon Buchanan, Jeffrey Buchhalter, Beate Diehl, Elizabeth Donner, Carl Faingold, Daniel Friedman, Christina Gross, Bin Gu, Franck Kalume, David Ryan King, Nuria Lecumberri, Susanne Mueller, William Nobis, Jeffrey Noebels, Terence O’Brien, Manoj Patel, George Richerson, Steven Schachter, Timothy Simeone, Ian Wenker   +34 more
wiley   +1 more source

Mixed housing with DBA/2 mice induces stress in C57BL/6 mice: implications for interventions based on social enrichment

Frontiers in Behavioral Neuroscience, 2014
Several behavioral interventions, based on social enrichment and observational learning are applied in treatment of neuropsychiatric disorders. However, the mechanism of such modulatory effect and the safety of applied methods on individuals involved in ...
Natalia eKulesskaya, Nina N Karpova, Li eMa, Li eTian, Vootele eVoikar   +4 more
doaj   +1 more source

Sex differences in voluntary running behavior between C57BL/6 and BALB/cJ mouse strains do not correspond to changes in VO2 and RER

Physiological Reports, Volume 13, Issue 19, October 2025.
Study and results overview. Abstract Exercise adaptations are influenced by sex and genetic background, contributing to variability in metabolic and physiological responses. This study investigates sex and strain‐specific differences following voluntary wheel running exercise training in submaximal and maximal oxygen consumption (VO2), respiratory ...
N. Amiri, H. Zhang, R. McMillan, R. W. Grange, J. C. Drake   +4 more
wiley   +1 more source

Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity-3

, 2011
Copyright information:Taken from "Variation in the cortical area map of C57BL/6J and DBA/2J inbred mice predicts strain identity"BMC Neuroscience 2005;6():18-18.Published online 17 Mar 2005PMCID:PMC1079866.Copyright © 2005 Airey et al; licensee BioMed ...
Katherine M Enzinger (71411), David C Airey (65999), Alicia I Robbins (71410), Christine E Collins (66002), Fangbai Wu (66000)   +4 more
core   +1 more source

A companion to the preclinical common data elements for rodent genetic epilepsy models. A report of the TASK3‐WG1B: Paediatric and genetic models working group of the ILAE/AES joint translational TASK force

Epilepsia Open, Volume 10, Issue S1, Page S40-S52, August 2025.
Abstract Rodent models of epilepsy remain the cornerstone of research into the mechanisms underlying genetic epilepsy. Reproducibility of experiments using these rodent models, occurring across a diversity of laboratories and commercial vendors, remains an issue impacting the cost‐effectiveness and scientific rigor of the studies performed.
Massimo Mantegazza, Stėphane Auvin, Melissa Barker‐Haliski, Anna‐Maria Katsarou, Hana Kubova, Aristea S. Galanopoulou, Bridgette Semple, Christopher A. Reid   +7 more
wiley   +1 more source

Features of DBA-g+ and DBA mice.

, 2015
(A) Expression of Gpnmb is observed in DBA-g+ but not DBA mice following a single injection of CCl4. However, (B) sequential changes in serum ALT levels and the degree of liver injury are not affected by the lack of Gpnmb-positive macrophages (original ...
Tsutomu Tamai (496424), Kazuaki Tabu (496423), Shinichi Hashimoto (829572), Akihiro Moriuchi (496425), Shiroh Tanoue (829573), Yoichiro Takami (829570), Yuko Morinaga (829571), Shuji Kanmura (496420), Kotaro Kumagai (496421), Hirofumi Uto (496418), Seiichi Mawatari (496417), Hirohito Tsubouchi (496428), Fumisato Sasaki (829569), Akio Ido (496419)   +13 more
core   +1 more source

Of mice and academics: examining the effect of openness on innovation [PDF]

, 2008
Scientific freedom and openness are hallmarks of academia: relative to their counterparts in industry, academics maintain discretion over their research agenda and allow others to build on their discoveries.
Fiona Murray, Aghion, Philippe, Scott Stern, Dewatripont, Mathias, Kolev, Julian, Kolev, J., Dewatripont, M., Stern, Scott, Philippe Aghion, Murray, F., Murray, Fiona, Julian Kolev, Mathias Dewatripont, Stern, S., Aghion, P.   +14 more
core   +1 more source