Results 51 to 60 of about 1,160,575 (212)
Characterization of the blood–brain barrier in genetically diverse laboratory mouse strains
Fluids and Barriers of the CNS, 2021 Background Genetic variation in a population has an influence on the manifestation of monogenic as well as multifactorial disorders, with the underlying genetic contribution dependent on several interacting variants.
Johanna Schaffenrath +4 more
doaj +1 more source
Journal of Neurochemistry, Volume 170, Issue 7, July 2026.Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We used a systematic meta‐analysis of public transcriptional profiling datasets to identify genes and functional gene sets that are differentially expressed ...
Eva M. Geoghegan +11 more
wiley +1 more source
PLoS Genetics, 2012 Atrio-ventricular conduction disease is a common feature in Mendelian rhythm disorders associated with sudden cardiac death and is characterized by prolongation of the PR interval on the surface electrocardiogram (ECG). Prolongation of the PR interval is
Elisabeth M Lodder +10 more
doaj +1 more source
Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice
BMC Neuroscience, 2007 Background Several neurodegenerative diseases are influenced by complex genetics that affect an individual's susceptibility, disease severity, and rate of progression.
Schlamp Cassandra L +3 more
doaj +1 more source
Anatomia, Histologia, Embryologia, Volume 55, Issue 2, March 2026.ABSTRACT The detailed anatomical situation of male stillborn cephalo‐thoracopagus twins in a wild ranging northern bat (Eptesicus nilssonii) is described by means of full body micro‐CT scans in high resolution with three‐dimensional computational reconstruction.
J. Meyer +5 more
wiley +1 more source
Sex Differences in Metabolite–Immune Circuits of Neuroinflammation
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Sex is a fundamental yet underexplored determinant of human neuroinflammation. Across autoimmune, neurodegenerative, and post‐infectious neurological syndromes, males and females exhibit consistent differences in disease vulnerability, progression, and immune tone.
Priyanka Saminathan +6 more
wiley +1 more source
Reactions to spatial and nonspatial change in two inbred strains of mice: Further evidence supporting the hippocampal dysfunction hypothesis in the DBA/2 strain [PDF]
Psychobiology, 1995 Mice belonging to the inbred C57BL/6 and DBA/2 strains were repeatedly exposed to a given spatial configuration of five objects contained in an open field. Locomotor activity, habituation of exploration, and reactivity to the displacement of some objects (spatial change) and to the substitution of a familiar object by a new one (nonspatial change) were
Ammassari Teul M +4 more
openaire +3 more sources
Memorias do Instituto Oswaldo Cruz, 1998 Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves +4 more
doaj +1 more source
Frontiers in Genetics, 2020 Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility were
Heja Aga +31 more
doaj +1 more source
Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]
PLoS ONE, 2014 The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen +9 more
doaj +1 more source