Results 51 to 60 of about 13,142 (173)

Helminth Parasites of Conventionally Maintained Laboratory Mice: II- Inbred Strains with an Adaptation of the Anal Swab Technique

Memorias do Instituto Oswaldo Cruz, 1998
Worm burdens recovered from inbred mice strains, namely C57Bl/6, C57Bl/10, CBA, BALB/c, DBA/2 and C3H/He, conventionally maintained in two institutional animal houses in the State of Rio de Janeiro, RJ, Brazil, were analyzed and compared, regarding their
Lucineide Gonçalves, Roberto Magalhães Pinto, J Júlio Vicente, Dely Noronha, Delir Corrêa Gomes   +4 more
doaj   +1 more source

Identification of Novel Potential Type 2 Diabetes Genes Mediating β-Cell Loss and Hyperglycemia Using Positional Cloning

Frontiers in Genetics, 2020
Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility were
Heja Aga, Heja Aga, Nicole Hallahan, Nicole Hallahan, Pascal Gottmann, Pascal Gottmann, Markus Jaehnert, Markus Jaehnert, Sophie Osburg, Sophie Osburg, Gunnar Schulze, Gunnar Schulze, Anne Kamitz, Anne Kamitz, Danny Arends, Gudrun Brockmann, Tanja Schallschmidt, Tanja Schallschmidt, Sandra Lebek, Sandra Lebek, Alexandra Chadt, Alexandra Chadt, Hadi Al-Hasani, Hadi Al-Hasani, Hans-Georg Joost, Hans-Georg Joost, Annette Schürmann, Annette Schürmann, Annette Schürmann, Heike Vogel, Heike Vogel, Heike Vogel   +31 more
doaj   +1 more source

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology. [PDF]

PLoS ONE, 2014
The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility.
Jianlin Chen, Hongbo Zhang, Zhou Zhou, Zhangsheng Yang, Yiling Ding, Zhiguang Zhou, Edward Zhong, Bernard Arulanandam, Joel Baseman, Guangming Zhong   +9 more
doaj   +1 more source

Technetium-99m pyrophosphate uptake in spontaneously occurring perimyocardial lesions in an inbred strain of DBA/2 mice.

Japanese Circulation Journal, 1982
The spontaneous occurrence of perimyocardial calcification localized in the right ventricle has been reported in an inbred strain of DBA/2 mice. In this paper we examined the correlation between the myocardial uptake ratio of technetium-99m pyrophosphate (99mTc-PYP) and pathological findings in these mice ranging in age from one to 12 months and became
YOSHIDA, AKIRA, MATSUMORI, AKIRA, KAWAI, CHUICHI, TORIZUKA, KANJI   +3 more
openaire   +3 more sources

PAC‐FOS: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

Epilepsia, Volume 66, Issue 12, Page 4983-4995, December 2025.
Abstract Objective Central to the development of novel antiseizure medications (ASMs) is testing of antiseizure activity in preclinical models. Although various well‐established models exist, their predictive validity across the spectrum of clinical epilepsies has been less clear.
Lyndsey L. Anderson, Kristopher M. Kahlig, Melissa L. Barker‐Haliski, Lillian G. Matthews, Hamish D. Toop, Brian Hannigan, Jacqueline French, H. Steve White, Marcio Souza, Steven Petrou   +9 more
wiley   +1 more source

Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis

Bone Research
Rheumatoid arthritis (RA) is an autoimmune disease. Early studies hold an opinion that gut microbiota is environmentally acquired and associated with RA susceptibility.
Hongzhen Chen, Xuekun Fu, Xiaohao Wu, Junyi Zhao, Fang Qiu, Zhenghong Wang, Zhuqian Wang, Xinxin Chen, Duoli Xie, Jie Huang, Junyu Fan, Xu Yang, Yi Song, Jie Li, Dongyi He, Guozhi Xiao, Aiping Lu, Chao Liang   +17 more
doaj   +1 more source

Delayed and transient increase of adult hippocampal neurogenesis by physical exercise in DBA/2 mice.

PLoS ONE, 2013
This study builds on the findings that physical activity, such as wheel running in mice, enhances cell proliferation and neurogenesis in the adult hippocampus of the common mouse strain C57BL/6, and that the baseline level of neurogenesis varies by ...
Rupert W Overall, Tara L Walker, Odette Leiter, Sina Lenke, Susann Ruhwald, Gerd Kempermann   +5 more
doaj   +1 more source

Quantitative Trait Loci Analysis of Structural and Material Skeletal Phenotypes in C57BL/6J and DBA/2 Second-Generation and Recombinant Inbred Mice [PDF]

Journal of Bone and Mineral Research, 2005
Abstract QTL analyses identified several chromosomal regions influencing skeletal phenotypes of the femur and tibia in BXD F2 and BXD RI populations of mice. QTLs for skeletal traits co-located with each other and with correlated traits such as body weight and length, adipose mass, and serum alkaline phosphatase ...
Lang, Dean H., Sharkey, Neil A., Mack, Holly A. (R18996), Vogler, George P., Vandenbergh, David J., Blizard, David A., Stout, Joseph T., McClearn, Gerald E.   +7 more
openaire   +3 more sources

Mouse development - From oocyte to stem cells

European Journal of Histochemistry, 2014
This is a really good book for those who love developmental biology: young fellows at the beginning of their careers, esteemed professors, historians of science or fully active leading researchers.
Manuela Monti
doaj   +1 more source

Nicotinamide nucleotide transhydrogenase deficiency and genetic susceptibility to high glucose‐mediated peritoneal injury in mice

Physiological Reports, Volume 13, Issue 22, November 2025.
High‐glucose peritoneal dialysis (PD) fluid induces oxidative stress, inflammation, and fibrosis in the peritoneum. In vivo, Nnt‐deficient C57BL/6J mice showed significantly reduced PD‐induced peritoneal injury, inflammation, and fibrosis compared with Nnt‐competent C57BL/6N controls.
Margarete C. Ohse, Song Rong, Sonja Schmidt, Michael S. Balzer, Christoph Nikolin, Sibylle von Vietinghoff, Hermann Haller, Kai M. Schmidt‐Ott, Yulia Kiyan, Nelli Shushakova   +9 more
wiley   +1 more source