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A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism

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Maternal Behavior in Female C57BL/6J and DBA/2J Inbred Mice

Physiology & Behavior, 1999
Inbred strains of mice exhibit different patterns of maternal behavior, providing material for studies of genetic influences on the expression of maternal behavior. Beginning 1 day after birth, maternal behavior was recorded daily for 14 days in the first and second litters of C57BL/6J (B6) and DBA/2J (D2) mothers.
R E, Brown   +3 more
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Social approach–avoidance behavior of inbred mouse strains towards DBA/2 mice

Brain Research, 2004
Little is known about the genetics of social approach-avoidance behaviors. We measured social approach-avoidance of prepubescent female C57BL/6J, DBA/2J, FVB/NJ, AKR/J, A/J, and BALB/cJ mice towards prepubescent DBA/2J female mice. C57BL/6J mice showed the greatest predominance of approach, while BALB/cJ mice showed the greatest predominance of ...
Edward S, Brodkin   +3 more
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Discriminative stimulus effects of 5.6mg/kg pregnanolone in DBA/2J and C57BL/6J inbred mice

Alcohol, 2005
Neurosteroids represent a class of endogenous compounds that exert rapid, nongenomic effects through neurotransmitter receptor systems such as gamma-aminobutyric acid(A) (GABA(A)). Two neurosteroids, allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) and pregnanolone (3alpha-hydroxy-5beta-pregnan-20-one), possess anxiolytic and sedative properties
Erin E, Shannon   +2 more
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A note on behavioral divergence between two substrains of DBA/2 inbred mice

Behavior Genetics, 1986
Adult male mice from the substrains DBA/2JNmg and DBA/2J were individually placed into a novel environment and compared for nine behavioral components. The substrains differed in three vertically oriented exploratory acts, the latter showing the highest rates.
J H, van Abeelen, R N, Hughes
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Discriminative Stimulus Effects of Ethanol in C57BL/6J and DBA/2J Inbred Mice

Alcoholism: Clinical and Experimental Research, 2002
Background: Two of the most widely used mouse strains for studying the behavioral effects of ethanol are C57BL/6J (B6) and DBA/2J (D2) mice. These strains exhibit marked differences in behavioral and physiological responses to ethanol. The subjective discriminative stimulus effects of ethanol may play a role in ethanol abuse, but the discriminative ...
Keith L, Shelton, Kathleen A, Grant
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Genotypic differences in mesolimbic enkephalin gene expression in DBA/2J and C57BL/6J inbred mice

European Journal of Pharmacology, 1996
The DBA/2J and C57BL/6J (herein referred to as DBA and C57) inbred mouse strains exhibit low and high predispositions for voluntary ethanol consumption, respectively, but the neurobiological basis underlying this differential drug vulnerability remains poorly understood. Comparison of endogenous brain proenkephalin gene expression showed the C57 mouse,
G Y, Ng, B F, O'Dowd, S R, George
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PCBs and PBBs: Biologic and toxic effects on C57BL/6J and DBA/2J inbred mice

Toxicology, 1984
Treatment of genetically inbred "responsive" C57BL/6J and "non-responsive" DBA/2J mice with Aroclor 1254 or fireMaster BP-6 resulted in the induction of hepatic microsomal benzo[a]pyrene hydroxylase only in the former mouse strain and aminopyrine N-demethylase in both strains of mice.
L W, Robertson   +5 more
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Behavioral sensitization to drug stimulant effects in C57BL/6J and DBA/2J inbred mice.

Behavioral Neuroscience, 1994
Common features shared by addictive drugs have been difficult to identify. One ubiquitous effect of these drugs is psychomotor stimulation. Further, repeated exposure commonly results in sensitization to drug stimulant effects. This study evaluates sensitization to drugs from several drug classes in C57BL/6J and DBA/2J inbred strain mice.
T J, Phillips   +2 more
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Genetic analysis of cerebellar folial pattern in crosses of C57BL/6J and DBA/2J inbred mice

Brain Research, 1993
Variation in the cerebellar folial pattern of mice is influenced by genetic elements [Inouye, M. and Oda, S., J. Comp. Neurol., 190 (1980) 357-362]. In crosses of C57BL/6J and DBA/2J inbred mice, the presence or absence of a specific fissure, the intraculminate fissure, is largely determined by a single genetic locus (Cfp-1), which is located on distal
P E, Neumann   +3 more
openaire   +2 more sources

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