Results 281 to 290 of about 3,684,237 (327)

Transgenic Mice With Immunoglobulin Genes

Annual Review of Immunology, 1987
Immunoglobulin (Ig) genes encode antibody molecules expressed exclu­ sively in the B-Iymphocyte lineage. The most immature identifiable cells of the B-cell lineage, pre-B cells, give rise to B cells that differentiate terminally into antibody secreting plasma cells.
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Transgenic Mice Modelling

2012
Although the prion protein (PrP) was discovered in the early 1980s, there is still a considerable lack of knowledge of the normal function of the PrP protein and its precise role in the infectious process of transmissible spongiform encephalopathies (TSEs) or prion diseases.
Abigail B. Diack, Rona Wilson, Enrico Cancellotti, Barry Bradford, Matthew Bishop, Jean C. Manson   +5 more
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Transgenic mice

Cell, 1985
R D, Palmiter, R L, Brinster
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Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Science, 1996
K. Hsiao, P. Chapman, S. Nilsen, C. Eckman, Y. Harigaya, S. Younkin, Fusheng Yang, G. Cole   +7 more
semanticscholar   +1 more source

Oxytocin transgenic mice.

Advances in experimental medicine and biology, 1996
We have compared the expression patterns in transgenic mice of bovine oxytocin constructs consisting of the 0.9 kilobase pair (kbp) structural gene flanked by varying lengths of upstream and downstream sequences. Over 200 offspring were derived from fertilized one-cell mouse eggs injected with construct bOT6.5, which consists of 3 kbp of upstream ...
D, Murphy, M Y, Ho
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Transgenic Mice

Otolaryngologic Clinics of North America, 1992
Rick A. Friedman, Allen F. Ryan
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Histological Examination of Transgenic Mice

2003
Histological examination is important to detect and differentiate among different types of tissue changes at the microscopic level. An enlarged organ can be hyperplastic, hypertrophied, or neoplastic. It can also be merely inflamed or infected. Only a histological examination can differentiate among the various growth disturbances and pathological ...
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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Nature, 1995
D. Games, David John Adams, Ree Alessandrini, R. Barbour, Patricia Borthelette, C. Blackwell, Tony Carr, J. Clemens, T. Donaldson, F. Gillespie, T. Guido, S. Hagopian, K. Johnson-wood, K. Khan, Mike Lee, P. Leibowitz, I. Lieberburg, S. Little, E. Masliah, L. McConlogue, M. Montoya-Zavala, L. Mucke, L. Paganini, E. Penniman, M. Power, D. Schenk, P. Seubert, B. Snyder, F. Soriano, H. Tan, J. Vitale, S. Wadsworth, B. Wolozin, Jun Zhao   +33 more
semanticscholar   +1 more source

Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements

Immunology and Cell Biology, 1998
M. Barnden, J. Allison, W. Heath, F. Carbone   +3 more
semanticscholar   +1 more source

Transgenic RNA Interference in Mice

2008
RNA interference (RNAi) is a powerful tool in deciphering gene function. It has been used extensively, especially in cultured mammalian cells. We have shown that RNAi-induced gene silencing can be generated in mice. With conventional transgenic techniques, shRNA-expressing constructs can be introduced into one-cell mouse embryos. The transgenic animals
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