Results 101 to 110 of about 6,539,286 (354)

The gut microbiota influences skeletal muscle mass and function in mice

open access: yesScience Translational Medicine, 2019
Transplanting the gut microbiota of pathogen-free mice into germ-free mice improves skeletal muscle mass and strength. Of microbial metabolites and muscle Skeletal muscle is important not only for locomotion but also for regulating metabolic function ...
Shawon Lahiri   +18 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Comprehensive mapping and modelling of the rice regulome landscape unveils the regulatory architecture underlying complex traits

open access: yesNature Communications
Unraveling the regulatory mechanisms that govern complex traits is pivotal for advancing crop improvement. Here we present a comprehensive regulome atlas for rice (Oryza sativa), charting the chromatin accessibility across 23 distinct tissues from three ...
Tao Zhu   +12 more
doaj   +1 more source

Management for the transformation of a Historical City into a MICE City supporting the idea of MICE business in AEC. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
This mixed method research investigated the measures that had been taken in order to transform a historical city into a MICE city in order to cater to MICE business, which has been rampaging under the prevailing AEC.
Asst. Prof. Dr. Thirachaya Chaigasem
doaj  

Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. [PDF]

open access: yes, 1990
Breaking the state of immunological unresponsiveness of tumor-bearing individuals to cancer is a prerequisite for active or passive tumor-specific immunotherapy.
Koeppen, H   +5 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Evaluation of anti-inflammatory, anti-nociceptive, and anti-pyretic potential of hydroalcoholic extract of Trifolium pratense in mice

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery, 2019
Introduction: There are some reports in traditional medicine concerning the anti-inflammatory, anti-nociceptive and anti-pyretic effects of Trifolium pretense (red clover).
Parandin R
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Evaluating the Heat of Hydration, Conductivity, and Microstructural Properties of Cement Composites with Recycled Concrete Powder

open access: yesBuildings
This study investigates the effects of incorporating recycled concrete powder (RCP) as a supplementary cementitious material in Portland cement composites at replacement levels of 5–30% by weight.
Damir Barbir   +3 more
doaj   +1 more source

Ready to be a host?: The potential development guidelines of sport tourism in Buriram Province, Thailand [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2020
Tourism is a major industry in the world. Sport tourism is considered to be a part of tourism created through of the integration of sports and tourism.
Asst. Prof. Dr. Thirachaya Chaigasem   +1 more
doaj  

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