Results 131 to 140 of about 4,772,082 (338)
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed+8 more
wiley +1 more source
Motivation and work behavior in tourism-related businesses located on the Thai-Malaysian border during Thailand’s Reform Period. [PDF]
This survey research was aimed at 1) investigating motivation and work behavior in tourism-related businesses located on the Thai-Malaysian border; 2) comparing work behaviors within tour operator establishments versus those in hotel establishments; and ...
Asst. Prof. Dr. Aree Naipinit +2 more
doaj
Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]
The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
Phreatic groundwater, discovered easily around communities in the Kuta Raja Sub-district, is sourced from the subsurface and stored in saturated areas, where it flows naturally through seepage or jets.
Mice Putri Afriyani+5 more
doaj +1 more source
Experimental infection of rats and mice with the common intestinal Amoebae of man [PDF]
Walter Landauer
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Effect of PlGF-inhibition on survival in mice with hepatocellular carcinoma [PDF]
Background: Inhibition of angiogenesis is currently hot topic in the search for an effective treatment for hepatocellular carcinoma (HCC). Up till recently, the focus was mainly on VEGF, an important regulator in the pathologic and physiologic ...
Carmeliet, Peter+4 more
core +1 more source
Feinstein, R N+3 more
openaire +2 more sources