Results 131 to 140 of about 4,772,082 (338)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Motivation and work behavior in tourism-related businesses located on the Thai-Malaysian border during Thailand’s Reform Period. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
This survey research was aimed at 1) investigating motivation and work behavior in tourism-related businesses located on the Thai-Malaysian border; 2) comparing work behaviors within tour operator establishments versus those in hotel establishments; and ...
Asst. Prof. Dr. Aree Naipinit   +2 more
doaj  

Deletion of Cardiac miR-17-92 Cluster Increases Ischemia/ Reperfusion Injury via PTEN Upregulation [PDF]

open access: yes, 2017
The miR-17- 92 cluster is necessary for cell proliferation and development of the cardiovascular system. Deletion of this cluster leads to death in neonatal mice.
Prakash, Meeta B
core   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Phreatic Groundwater Quality Analysis Based on Physical and Chemical Parameters in Kuta Raja Sub-District

open access: yesForum Geografi
Phreatic groundwater, discovered easily around communities in the Kuta Raja Sub-district, is sourced from the subsurface and stored in saturated areas, where it flows naturally through seepage or jets.
Mice Putri Afriyani   +5 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Effect of PlGF-inhibition on survival in mice with hepatocellular carcinoma [PDF]

open access: yes, 2010
Background: Inhibition of angiogenesis is currently hot topic in the search for an effective treatment for hepatocellular carcinoma (HCC). Up till recently, the focus was mainly on VEGF, an important regulator in the pathologic and physiologic ...
Carmeliet, Peter   +4 more
core   +1 more source

Skin Homografts in Parabiotic Mice [PDF]

open access: bronze, 1959
A Skowron-Cendrzak   +1 more
openalex   +1 more source

ACATALASEMIC MICE [PDF]

open access: yesProceedings of the National Academy of Sciences, 1964
Feinstein, R N   +3 more
openaire   +2 more sources

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