YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Targeting the NLRP3 inflammasome to attenuate spinal cord injury in mice [PDF]
, 2017 Wu Jiang +4 more
openalex +1 more source
Plasmalogens Eliminate Aging-Associated Synaptic Defects and Microglia-Mediated Neuroinflammation in Mice [PDF]
, 2022 Jinxin Gu +12 more
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Oral Delivery of IL-27 Recombinant Bacteria Attenuates Immune Colitis in Mice [PDF]
, 2013 Miranda L. Hanson +10 more
openalex +1 more source
Identity for cultural tourism of the Bueng Kan Province, Thailand. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 This study aimed to: 1) To study identities and cultural tourism potential in Bueng Kan province. 2) To study the participation of people in promoting cultural identities in Bueng Kan province.
Dr. Thirachaya Chaigassem +1 more
doaj
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer’s disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis [PDF]
, 2021 Hei-Jen Huang +8 more
openalex +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Exercise reduces activation of microglia isolated from hippocampus and brain of aged mice [PDF]
, 2013 Rachel A. Kohman +3 more
openalex +1 more source