Results 281 to 290 of about 4,155,608 (362)

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

The involvement of TRPV1 in the apoptosis of spermatogenic cells in the testis of mice with cryptorchidism. [PDF]

Cell Death Discov
Zhao Y, Wei J, Cheng P, Ma J, Liu B, Xiong M, Gao T, Yao J, Sun T, Li Z.   +9 more
europepmc   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

D-chiro-inositol effectively counteracts endometriosis in a mouse model. [PDF]

Mol Med
Placidi M, Casoli G, Vergara T, Bianchi A, Cocciolone D, Zaccardi S, Macchiarelli G, Palmerini MG, Tatone C, Bevilacqua A, Di Emidio G.   +10 more
europepmc   +1 more source

Machine stability and dosimetry for ultra‐high dose rate FLASH radiotherapy human clinical protocol

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The FLASH effect, induced by ultra‐high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and accurate dose delivery and to establish reliable detector systems, particularly for clinical trials needed to help the clinical transfer of FLASH‐
Patrik Gonçalves Jorge, Reiner Geyer, Rémy Kinj, Luis Schiappacasse, Wendy Jeanneret‐Sozzi, Jean Bourhis, Fernanda Herrera, François Bochud, Claude Bailat, Raphaël Moeckli   +9 more
wiley   +1 more source

A high-fructose diet leads to osteoporosis by suppressing the expression of Thrb and facilitating the accumulation of cholesterol. [PDF]

Cell Death Discov
Chen J, Jiang X.
europepmc   +1 more source

Optimized Mouse Model of Sepsis-Associated Encephalopathy: A Rational Standard Based on Modified SHIRPA Score and Neurobehaviors in Mice. [PDF]

CNS Neurosci Ther
Xin Y, Tian M, Pei X, Deng S, Wang Y, Zhao F, Behnisch T, Gao Y, Gong Y.   +8 more
europepmc   +1 more source

Fancy mice : their varieties, management, and breeding /

, 1896
An old fancier.
openalex   +2 more sources

Muscle fiber Myc is dispensable for muscle growth and its forced expression severely perturbs homeostasis. [PDF]

Nat Commun
Ham DJ, Semeraro M, Berger BM, McGowan TJ, Lin S, Maino E, Oliveri F, Rüegg MA.   +7 more
europepmc   +1 more source

Winnie Mice: A Chronic and Progressive Model of Ulcerative Colitis. [PDF]

Inflamm Bowel Dis
Chieppa M, De Santis S, Verna G.
europepmc   +1 more source