Results 291 to 300 of about 6,887,725 (399)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Impact of rAAV-shRNA treatment targeting mechanosensitive Ilk1 and Fermt2 in a mouse model of sepsis-induced muscle weakness. [PDF]

PLoS One
Pacolet A, Derese I, Pauwels L, Perre SV, Smits M, Van den Haute C, Derde S, Koppo K, Gijsbers R, Langouche L.   +9 more
europepmc   +1 more source

Ascorbic Acid: a Promising Memory-Enhancer in Mice

, 2003
Milind Parle, Dinesh Dhingra
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Furin-Mediated Cleavage of Zona Pellucida Proteins Is Essential for Oocyte Development. [PDF]

MedComm (2020)
Ruan T, Wang X, Zhang X, Wang Y, Jiang C, Wu S, Tian Y, Tang X, Ma J, Zhao S, Zhuo L, Liu M, Dai S, Wang Z, Xu W, Shen Y.   +15 more
europepmc   +1 more source

Female preproenkephalin-knockout mice display altered emotional responses

, 2001
André Ragnauth, Alwin G. Schuller, Maria A. Morgan, Johnny S.W. Chan, Sonoko Ogawa, John E. Pintar, Richard J. Bodnar, Donald W. Pfaff   +7 more
openalex   +2 more sources

Rapamycin in mice

Aging, 2017
openaire   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Antiviral and immune modulatory activities of STING agonists in a mouse model of persistent hepatitis B virus infection. [PDF]

PLoS Pathog
Wang Y, Wu S, Li X, Qiao L, Wang H, Yang G, Yan H, Wang K, Jiang JD, Li Y.   +9 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source