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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Nature, 2007C. O’Brien +3 more
semanticscholar +1 more source
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
Nature, 1994T. Lapidot +9 more
semanticscholar +1 more source
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Nature, 1992L. Donehower +6 more
semanticscholar +1 more source
Interleukin-10-deficient mice develop chronic enterocolitis
Cell, 1993R. Kühn +4 more
semanticscholar +1 more source
More hippocampal neurons in adult mice living in an enriched environment
Nature, 1997G. Kempermann, H. Kuhn, F. Gage
semanticscholar +1 more source
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Nature, 2006Taichi Hara +10 more
semanticscholar +1 more source
Effects of the obese gene product on body weight regulation in ob/ob mice.
Science, 1995M. Pelleymounter +6 more
semanticscholar +1 more source
2010
The use of genetically engineered mice has become a standard approach in order to study the physiological contribution of genes in a variety of life-science disciplines. Classical and conditional gene-targeting methods aimed at generating knock-out mice that lack gene products have been useful, but may be limited in their scope. If the gene of interest
openaire +2 more sources
The use of genetically engineered mice has become a standard approach in order to study the physiological contribution of genes in a variety of life-science disciplines. Classical and conditional gene-targeting methods aimed at generating knock-out mice that lack gene products have been useful, but may be limited in their scope. If the gene of interest
openaire +2 more sources