Results 71 to 80 of about 3,757,344 (237)
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
B cells in the human immune system (HIS) mice exhibit weak responses to external antigens, characterized by insufficient antigen‐specific B cell proliferation, low antibody titers, and a lack of differentiation into effector B cell subsets.
Haiqiao Sun +6 more
doaj +1 more source
Tourist behaviors and needs for the development of creative Thai traditional sports tourism marketing for special interest tourism [PDF]
This study aimed to investigate tourist behaviors and needs for the development of creative Thai traditional sports tourism to support special interest tourism.
Asst. Prof. Dr. Thirachaya Chaigasem +1 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Mehaničko recikliranje poliamidne niti za košnju: rješenje ili gubitak vremena? [PDF]
U ovom radu provedeno je mehaničko recikliranje niti za košnju u laboratorijskom dvopužnom ekstruderu. Procijenjen je utjecaj mehaničkog recikliranja na strukturu, toplinska svojstva i toplinsku postojanost materijala od kojeg su izrađene niti za košnju.
Miće Jakić +3 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
This study investigates the effects of incorporating recycled concrete powder (RCP) as a supplementary cementitious material in Portland cement composites at replacement levels of 5–30% by weight.
Damir Barbir +3 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Muon Ionization Cooling Experiment (MICE) is a strategic R&D project intended to demonstrate the only practical solution to providing high brilliance beams necessary for a neutrino factory or muon collider.
MICE Collaboration
core +1 more source

