Novel polymer micelle mediated co-delivery of doxorubicin and P-glycoprotein siRNA for reversal of multidrug resistance and synergistic tumor therapy [PDF]
Scientific Reports, 2016 Co-delivery of chemotherapeutics and siRNA with different mechanisms in a single system is a promising strategy for effective cancer therapy with synergistic effects.
Chun-ge Zhang +9 more
semanticscholar +2 more sources
Drug Delivery, 2019 Myricetin (Myr) is a naturally occurring flavonoid exhibiting diverse biological and pharmacological properties, but its characteristics such as water insolubility, poor aqueous stability, and poor bioavailability limit its clinical application ...
Fengyuan Sun +6 more
doaj +2 more sources
Development and Characterization of EGCG-Loaded TPGS/Poloxamer 407 Micelles with Evaluation of In Vitro Drug Release and In Vivo Pharmacokinetics and Tolerability Observations Following Oral Administration [PDF]
PharmaceuticsBackground: Epigallocatechin-3-gallate (EGCG), a potent green tea polyphenol, possesses significant therapeutic potential, but its clinical application is limited by poor gastrointestinal stability and low oral bioavailability.
Chee Ning Wong +6 more
doaj +2 more sources
Correlation of Polymer-drug Composition with Micelle Properties, Performance, and Cytotoxicity for the Oligoelectrolyte-mediated pH-triggered Release of Hydrophobic Drugs. [PDF]
Polymers (Basel)Hussain MS +4 more
europepmc +3 more sources
Localized high-concentration electrolytes get more localized through micelle-like structures [PDF]
Nature Materials, 2023 Liquid electrolytes in batteries are typically treated as macroscopically homogeneous ionic transport media despite having a complex chemical composition and atomistic solvation structures, leaving a knowledge gap of the microstructural characteristics ...
Corey M. Efaw +17 more
semanticscholar +1 more source
Development and optimization of TPGS/P84 mixed polymeric micelles: enhanced stability and anticancer effect of paclitaxel against tumor therapy [PDF]
Acta Poloniae Pharmaceutica, 2023 Mixed micelles (MMs), as a new targeted drug delivery system with high adjustability, have been widely studied in biomedicines. In order to study whether mixtures containing two different molecules have excellent targeted anti-tumor effect, MMs based on ...
Qi Huang +7 more
doaj +1 more source
Chemical Thermodynamics and Thermal Analysis, 2022 Through dielectric measurements of aqueous n-hexyltrimethylammonium bromide solutions, the structure and dynamics of ion-pairs, micelles, and water are investigated as functions of concentration and temperature. The frequency range of the study was ∼ 0.2
Nashiour Rohman +2 more
doaj +1 more source
Scientific Reports, 2023 In the current work, a new type of micelle is designed that has active connectivity in respond to exterior stimulus and the desired water solubility.
Leila Razavi +2 more
doaj +1 more source
Cascade Processes with Micellar Reaction Media: Recent Advances and Future Directions
Molecules, 2022 Reducing the use of solvents is an important aim of green chemistry. Using micelles self-assembled from amphiphilic molecules dispersed in water (considered a green solvent) has facilitated reactions of organic compounds.
Christina Tang, Bridget T. McInnes
doaj +1 more source
Molecules, 2021 Reports on fungicide-based agronanochemicals in combating disastrous basal stem rot disease in the oil palm industry are scant. Herein, we describe the potential of fungicide nanodelivery agents based on hexaconazole-micelle systems produced using three ...
Isshadiba Faikah Mustafa +4 more
doaj +1 more source