Results 1 to 10 of about 245,864 (373)

Development and Characterization of EGCG-Loaded TPGS/Poloxamer 407 Micelles with Evaluation of In Vitro Drug Release and In Vivo Pharmacokinetics and Tolerability Observations Following Oral Administration [PDF]

open access: yesPharmaceutics
Background: Epigallocatechin-3-gallate (EGCG), a potent green tea polyphenol, possesses significant therapeutic potential, but its clinical application is limited by poor gastrointestinal stability and low oral bioavailability.
Chee Ning Wong   +6 more
doaj   +2 more sources

Development and optimization of TPGS/P84 mixed polymeric micelles: enhanced stability and anticancer effect of paclitaxel against tumor therapy [PDF]

open access: yesActa Poloniae Pharmaceutica, 2023
Mixed micelles (MMs), as a new targeted drug delivery system with high adjustability, have been widely studied in biomedicines. In order to study whether mixtures containing two different molecules have excellent targeted anti-tumor effect, MMs based on ...
Qi Huang   +7 more
doaj   +1 more source

Dielectric Relaxation of Ion-pairs, Micelles and Hydration in Aqueous Hexyltrimethylammonium Bromide Solutions

open access: yesChemical Thermodynamics and Thermal Analysis, 2022
Through dielectric measurements of aqueous n-hexyltrimethylammonium bromide solutions, the structure and dynamics of ion-pairs, micelles, and water are investigated as functions of concentration and temperature. The frequency range of the study was ∼ 0.2
Nashiour Rohman   +2 more
doaj   +1 more source

Validation of an MD simulation approach for electrical field responsive micelles and their application in drug delivery

open access: yesScientific Reports, 2023
In the current work, a new type of micelle is designed that has active connectivity in respond to exterior stimulus and the desired water solubility.
Leila Razavi   +2 more
doaj   +1 more source

Cascade Processes with Micellar Reaction Media: Recent Advances and Future Directions

open access: yesMolecules, 2022
Reducing the use of solvents is an important aim of green chemistry. Using micelles self-assembled from amphiphilic molecules dispersed in water (considered a green solvent) has facilitated reactions of organic compounds.
Christina Tang, Bridget T. McInnes
doaj   +1 more source

Hexaconazole-Micelle Nanodelivery System Prepared Using Different Surfactants for Ganoderma Antifungal Application

open access: yesMolecules, 2021
Reports on fungicide-based agronanochemicals in combating disastrous basal stem rot disease in the oil palm industry are scant. Herein, we describe the potential of fungicide nanodelivery agents based on hexaconazole-micelle systems produced using three ...
Isshadiba Faikah Mustafa   +4 more
doaj   +1 more source

Micellar Antibiotics of Bacillus

open access: yesPharmaceutics, 2021
Members of the Bacillus genus, particularly the “Bacillus subtilis group”, are known to produce amphipathic lipopeptides with biosurfactant activity.
William T. Ferreira   +14 more
doaj   +1 more source

Efficient Treatment of Rheumatoid Arthritis by Degradable LPCE Nano-Conjugate-Delivered p65 siRNA

open access: yesPharmaceutics, 2022
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases worldwide, causing severe cartilage damage and disability. Despite the recent progress made in RA treatment, limitations remain in achieving early and efficient therapeutic ...
Xiaohua Chen   +7 more
doaj   +1 more source

pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]

open access: yesRoyal Society Open Science, 2018
In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou   +3 more
doaj   +1 more source

Use of Micellar Delivery Systems to Enhance Curcumin’s Stability and Microbial Photoinactivation Capacity

open access: yesFoods, 2021
Microbial photoinactivation using ultraviolet (UV) or visible light can be enhanced by photosensitizers. This study assessed the efficacy of encapsulating a food-grade photosensitizer (curcumin) in surfactant micelles on its water dispersibility ...
Victor Ryu   +5 more
doaj   +1 more source

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