Results 21 to 30 of about 2,728 (198)

Polymicellar-based drug delivery systems for use in nanodentistry, oral and cranio-maxillo-facial oncology [PDF]

Biofunctional Materials, 2023
Polymer-based therapeutics is a precipitously-growing Research, Developmentand Innovation (R&D&I) translational field of bioengineering for biomedicine.
Ziyad S Haidar
doaj   +1 more source

Atomic Model and Micelle Dynamics of QS-21 Saponin

Molecules, 2014
QS-21 is a saponin extracted from Quillaja saponaria, widely investigated as a vaccine immunoadjuvant. However, QS-21 use is mainly limited by its chemical instability, significant variety in molecular composition and low tolerance dose in mammals. Also,
Conrado Pedebos, Laércio Pol-Fachin, Ramon Pons, Cilâine V. Teixeira, Hugo Verli   +4 more
doaj   +1 more source

Multipotent Poly(Tertiary Amine‐Oxide) Micelles for Efficient Cancer Drug Delivery

Advanced Science, 2022
The cancer drug delivery process involves a series of biological barriers, which require the nanomedicine to exhibit different, even opposite properties for high therapeutic efficacy.
Jiajia Xiang, Yihuai Shen, Yifan Zhang, Xin Liu, Quan Zhou, Zhuxian Zhou, Jianbin Tang, Shiqun Shao, Youqing Shen   +8 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Designing the structure of cationic star-shaped trimeric surfactants most active in micelle formation using molecular connectivity indices

Scientific Reports
A model expressing the relationship between the logarithm of critical micelle concentration of cationic star-shaped trimeric surfactants and topological indices was obtained using only molecular connectivity indices.
Anna Mozrzymas
doaj   +1 more source

Exploring the Antioxidant Properties of Citrus limon (Lemon) Peel Ultrasound Extract after the Cloud Point Extraction Method

Biomass
Each year, a substantial amount of food is discarded around the globe. A significant portion of this waste consists of by-products derived from Citrus fruits such as lemons.
Vassilis Athanasiadis, Theodoros Chatzimitakos, Martha Mantiniotou, Eleni Bozinou, Stavros I. Lalas   +4 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Mechanisms of microbial photoinactivation by curcumin’s micellar delivery

Frontiers in Food Science and Technology
Introduction: Microbial photoinactivation using UV light can be enhanced by the addition of food-grade photosensitizers (PSs), such as curcumin. Micellization of curcumin can improve its stability and antimicrobial activity.
Victor Ryu, Mrinalini Ghoshal, Piyanan Chuesiang, Silvette Ruiz-Ramirez, Lynne McLandsborough, Maria G. Corradini   +5 more
doaj   +1 more source

Photo‐Degradable Polyester Networks and Multi‐Photon Printed Objects Based on Cyclic Ketene Acetals

Advanced Functional Materials, EarlyView.
The current work introduces a photoreversible polyester network derived from radical ring‐opening polymerization of cyclic ketene acetals. It combines photoreversible cross‐linking with initiator‐free multi‐photon printing. Reversible network formation, tunable mechanical properties, and selective degradation highlight its potential as a versatile ...
Till Meissner, Julian Fanelli, Vinh Xuan Truong, Rob Jones, Jens Gaitzsch, Christopher Barner‐Kowollik   +5 more
wiley   +1 more source