Results 41 to 50 of about 50,903 (257)
Advanced Functional Materials, EarlyView.A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia +12 more
wiley +1 more source
Bicomponent polymeric micelles for pH-controlled delivery of doxorubicin
Drug Delivery, 2020 Stimuli-responsive drug delivery systems (DDSs) are expected to realize site-specific drug release and kill cancer cells selectively. In this study, a pH-responsive micelle was designed utilizing the pH-sensitivity of borate bonds formed between dopamine
Chunyun Wang +9 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Oligomerizing Pluronic triblock copolymers provides a processing strategy for tuning the mechanical properties and stimuli‐responsive behaviors of micellar hydrogels. Varying oligomer fraction produces hydrogels spanning brittle to highly extensible responses; maintaining micellar architectures enables cooling‐induced reverse thermal shape memory and ...
Gourav Kumbhojkar +8 more
wiley +1 more source
PharmaceuticsBackground: Epigallocatechin-3-gallate (EGCG), a potent green tea polyphenol, possesses significant therapeutic potential, but its clinical application is limited by poor gastrointestinal stability and low oral bioavailability.
Chee Ning Wong +6 more
doaj +1 more source
Drug Delivery, 2020 A delivery system based on l-carnitine (LC) conjugated chitosan (CS)-stearic acid polymeric micelles has been developed for improving the oral bioavailability of paclitaxel (PTX) through targeting intestinal organic cation/carnitine transporter 2 (OCTN2).
Tan Yang +6 more
doaj +1 more source
Drug Delivery, 2021 Multidrug resistance (MDR) and lack of targeting specificity are the main reasons why traditional drug therapies fail and produce toxic side effects in cancer chemotherapy. In order to increase targeting specificity and maximize therapeutic efficacy, new
Yawen Zhang +6 more
doaj +1 more source
One‐Step Curcumin‐Mediated Multiphoton Lithography for Bioactive 3D Scaffolds
Advanced Functional Materials, EarlyView.Curcumin‐mediated multiphoton lithography enables one‐step fabrication of highly architected complex gelatin methacryloyl scaffolds by exploiting curcumin as a multifunctional bioactive photoinitiator. The resulting 3D structures support mesenchymal stem cell adhesion, proliferation, and migration, while exhibiting dual antibacterial activity through ...
Myrto Charitaki +7 more
wiley +1 more source
Charge‐Tunable Coacervate Micelles for Separator Engineering in Lithium‐Sulfur Batteries
Advanced Functional Materials, EarlyView.A separator engineering strategy based on charge‐tunable complex coacervate core micelles (C3Ms) is presented to form an ion‐selective layer regulating polysulfide transport in Li–S batteries. The micelles enable uniform adsorption onto commercial polypropylene separators and infiltration throughout the internal pore network, suppressing polysulfide ...
Yongsheng Zhang +11 more
wiley +1 more source
Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine
Pharmaceuticals, 2023 Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.We present a scalable EC/TC hybrid smart window using a DCPE that enables tunable solar modulation (ΔTsol:15–43%), fast electrochromic switching (<90 s), and strong thermal blocking (10–14°C reduction). HPMC improves thermal stability, while an optimized ISL enhances EC performance.
Soyeon Kim +4 more
wiley +1 more source