Results 101 to 110 of about 72,556 (306)

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao   +11 more
wiley   +1 more source

New micelle myricetin formulation for ocular delivery: improved stability, solubility, and ocular anti-inflammatory treatment

open access: yesDrug Delivery, 2019
Myricetin (Myr) is a naturally occurring flavonoid exhibiting diverse biological and pharmacological properties, but its characteristics such as water insolubility, poor aqueous stability, and poor bioavailability limit its clinical application ...
Fengyuan Sun   +6 more
doaj   +1 more source

A novel temperature-responsive micelle for enhancing combination therapy

open access: yes, 2016
Cheng-Liang Peng,1,* Yuan-I Chen,2,3,* Hung-Jen Liu,2 Pei-Chi Lee,2 Tsai-Yueh Luo,1 Ming-Jium Shieh2,3 1Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan, 2Institute of Biomedical Engineering, College of Medicine and College of
Peng CL   +5 more
core  

Micelle-assisted fabrication of gel-like PEDOT microspheres: in situ observation of the growth process

open access: yes, 2011
Novel gel-like poly(ethylene dioxythiophene) (PEDOT) microspheres were fabricated via micelle-mediated polymerization from room temperature ionic liquids (RTILs).
Wang, D (王栋)   +13 more
core   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

open access: yesAdvanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim   +9 more
wiley   +1 more source

A Combined Self-Assembled Drug Delivery for Effective Anti-Breast Cancer Therapy

open access: yesInternational Journal of Nanomedicine, 2021
Hairong Wang, Yawen Zhang, Xiangle Zeng, Wenjun Pei, Ranran Fan, Yushuai Wang, Xiu Wang, Jianchun Li School of Pharmacy, Bengbu Medical College, Bengbu, 233030, People’s Republic of ChinaCorrespondence: Jianchun LiSchool of Pharmacy, Bengbu Medical
Wang H   +7 more
doaj  

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

open access: yesAdvanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib   +8 more
wiley   +1 more source

Large‐Diameter DNA‐Scaffolded Nanopores Enabled by Loosely Packed Peptides for Single‐Molecule Sensing

open access: yesAngewandte Chemie, EarlyView.
A nanopore composed of transmembrane peptides and a DNA scaffold that assists peptide assembly was constructed. By employing peptides containing the unnatural amino acid 2‐aminoisobutyric acid (Aib), which promotes loose packing between helices, a large‐diameter nanopore was achieved.
Zugui Peng   +3 more
wiley   +2 more sources

Injectable Thermoresponsive Dual Nanocarrier Hydrogel for Local Tacrolimus Delivery with a Two-Phase Release Profile

open access: yesPharmaceutics
Background: Overexpression of immune cell populations leads to self-amplifying cytokine loops, contributing to chronic inflammation in both allograft rejection and autoimmune conditions.
Sanjida Ahmed Srishti   +4 more
doaj   +1 more source

Micelle-enhanced flow injection analysis

open access: yesReviews in Analytical Chemistry, 2018
Surface-active agents are organic compounds of amphiphilic nature. When the concentration of surfactants is higher than a certain value, the monomers adhere to form well-defined aggregates known as micelles.
Abdeldaim Dalia T., Mansour Fotouh R.
doaj   +1 more source

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