Results 81 to 90 of about 2,728 (198)

A Combined Self-Assembled Drug Delivery for Effective Anti-Breast Cancer Therapy

International Journal of Nanomedicine, 2021
Hairong Wang, Yawen Zhang, Xiangle Zeng, Wenjun Pei, Ranran Fan, Yushuai Wang, Xiu Wang, Jianchun Li School of Pharmacy, Bengbu Medical College, Bengbu, 233030, People’s Republic of ChinaCorrespondence: Jianchun LiSchool of Pharmacy, Bengbu Medical
Wang H, Zhang Y, Zeng X, Pei W, Fan R, Wang Y, Wang X, Li J   +7 more
doaj  

A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

Advanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan, Junyang Chen, Xingmin Chen, Zengyi Fang, Yuanzhen Mi, Pingjin Zou, Shunlian Fu, Huakang Li, Ke Xu, Bing Lin, Jinyi Lang, Meihua Chen   +11 more
wiley   +1 more source

Micelle-enhanced flow injection analysis

Reviews in Analytical Chemistry, 2018
Surface-active agents are organic compounds of amphiphilic nature. When the concentration of surfactants is higher than a certain value, the monomers adhere to form well-defined aggregates known as micelles.
Abdeldaim Dalia T., Mansour Fotouh R.
doaj   +1 more source

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Solubilization of Insoluble and Poorly-Water Soluble Drugs in Micellar Systems

Pharmedicine Journal
Introduction: This study investigates the micellar solubilization of several insoluble and poorly soluble drugs—clopidogrel bisulfate, ganciclovir sodium, miconazole nitrate, brinzolamide, brimonidine tartarate, and dexamethasone—using sodium dodecyl ...
Sinem Gokturk, Cuneyt Toprak
doaj   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Structural Characterization of Ordered Mesoporous Silica Prepared by a Sol–Gel Process Using Urea-Based Cationic Gemini Surfactants

Gels
Mesoporous silica nanoparticles have been synthesized through sol–gel synthesis in basic conditions. Gemini surfactants having urea in the headgroups were used as pore-forming agents.
Sarvarjon Kurbonov, Zsolt Czigány, Zoltán Kovács, László Péter, Martin Pisárčik, Miloš Lukáč, Manfred Kriechbaum, Vasyl Ryukhtin, Ana-Maria Lacrămă, László Almásy   +9 more
doaj   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source