Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
Multidrug resistance (MDR) and lack of targeting specificity are the main reasons why traditional drug therapies fail and produce toxic side effects in cancer chemotherapy. In order to increase targeting specificity and maximize therapeutic efficacy, new
Yawen Zhang +6 more
doaj +1 more source
A new approach to high resolution, high contrast electron microscopy of macromolecular block copolymer assemblies [PDF]
Determining the structure of macromolecular samples is vital for understanding and adapting their function. Transmission electron microscopy (TEM) is widely used to achieve this, but, owing to the weak electron scattering cross-section of carbon, TEM ...
Allen +36 more
core +1 more source
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Catalytic polymeric nanoreactors : more than a solid supported catalyst [PDF]
Polymeric nanostructures can be synthesized where the catalytic motif is covalently attached within the core domain and protected from the environment by a polymeric shell.
Bosman, Liu, Wang, Yan
core +2 more sources
Tailoring the Properties of Functional Materials With N‐Oxides
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich +5 more
wiley +1 more source
Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine
Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang +3 more
doaj +1 more source
Advances in Stimuli‐Responsive Organic Materials and Polymers toward Intelligent CO2 Capture
Schematic illustration of the relationship between different stimuli and stimuli‐responsive organic materials and polymers for carbon dioxide (CO2) capture. Main stimuli include redox, pH, magnetism, temperature, light, and pressure. Furthermore, multi‐responsive materials, due to their high adaptability and scalability in complex environments, are ...
Jian Zhou +2 more
wiley +1 more source
Feasibility study of naphthalene removal: Naphthalene solubilization in aqueous solutions of a triblock copolymer of ethylene oxide and 1,2-butylene oxide, E64B20E64 [PDF]
Block copolymer E64B20E64, where E denotes oxyethylene, OCH2CH2, B denotes oxybutylene, OCH2CH (C2H5), and the subscripts denote number-average block lengths in repeat units, was synthesized by sequential anionic polymerization.
Colin Booth +2 more
doaj
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors.
Micelles have been employed to encapsulate the supramolecular assembly of quantum dots with palladium(II) porphyrins for the quantification of O2 levels in aqueous media and in vivo.
Christopher M. Lemon +9 more
semanticscholar +1 more source

