Results 51 to 60 of about 246,667 (372)

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

Dasatinib self-assembled nanoparticles decorated with hyaluronic acid for targeted treatment of tumors to overcome multidrug resistance

Drug Delivery, 2021
Multidrug resistance (MDR) and lack of targeting specificity are the main reasons why traditional drug therapies fail and produce toxic side effects in cancer chemotherapy. In order to increase targeting specificity and maximize therapeutic efficacy, new
Yawen Zhang, Xiangle Zeng, Hairong Wang, Ranran Fan, Yike Hu, Xuejie Hu, Jianchun Li   +6 more
doaj   +1 more source

Interfaces in Diblocks: A Study of Miktoarm Star Copolymers

, 2004
We study AB$_n$ miktoarm star block copolymers in the strong segregation limit, focussing on the role that the AB interface plays in determining the phase behavior.
Balagurusamy V. S. K., Ball R. C., Bates F. S., Beyer F. L., Beyer F. L., Davidock D. A., Discher D. E., Fredrickson G. H., Fredrickson G. H., Gido S. P., Goveas J. L., Grason G. M., Helfand E., Leibler L., Lescanec R. L., Li Y., Likhtman A. E., Likhtman A. E., Maldovan M., Matsen M. W., Matsen M. W., Matsen M. W., Matsen M. W., Matsen M. W., Matsen M. W., Milner S. T., Milner S. T., Milner S. T., Olmsted P. D., Park M., Percec V., Pochan D. J., Semenov A. N. Zh., Thomas E. L., Thurn-Albrecht T., Tselikas Y., Vavasour J. D., Weaire D., Yang L., Ziherl P., Ziherl P.   +40 more
core   +1 more source

New generation of electrochemical immunoassay based on polymeric nanoparticles for early detection of breast cancer [PDF]

, 2017
Screening and early diagnosis are the key factors for the reduction of mortality rate and treatment cost of cancer. Therefore, sensitive and selective methods that can reveal the low abundance of cancer biomarkers in a biological sample are always ...
Al-Hetlani, Entesar, Alrefae, Tareq, Aouabdi, Sihem, Leo Chen, Liaohai, Mouffouk, Fouzi, Serrai, Hacene   +5 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Cross-linking of micelles by gemini surfactants

, 2000
We investigate the effects of gemini surfactants, telechelic chain and lipids on the nature of micelles formed by conventional single-tail surfactants in water by carrying out Monte Carlo simulations. In a mixture of gemini and single-tail surfactants in
Chowdhury, Debashish, Flimm, Oliver, Kremer, Kurt, Maiti, Prabal K., Stauffer, Dietrich   +4 more
core   +1 more source

Tailoring the Properties of Functional Materials With N‐Oxides

Advanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich, Michelle Kobus, Shirin Mesgarha, Erica Moretto, Laurens Grosche, Wolfgang Maison   +5 more
wiley   +1 more source

Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine

Pharmaceuticals, 2023
Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang, Keerthi Atluri, Amit K. Tiwari, R. Jayachandra Babu   +3 more
doaj   +1 more source

Mesoporous Carbon Thin Films with Large Mesopores as Model Material for Electrochemical Applications

Advanced Functional Materials, EarlyView.
Mesoporous carbon thin films possessing 70 nm mesopores are prepared on titanium substrates by soft templating of resol resins with a self‐synthesized poly(ethylene oxide)‐block‐poly(hexyl acrylate) block copolymer. A strategy to avoid corrosion of the metal substrate is presented, and the films are extensively characterized in terms of morphology ...
Lysander Q. Wagner, Joshua Schober, Pascal Dippell, Chantal Glatthaar, Smail Mekhilef, David Schäfer, Hannes Hergert, Marcus Rohnke, Matthias T. Elm, Bernd M. Smarsly   +9 more
wiley   +1 more source

Feasibility study of naphthalene removal: Naphthalene solubilization in aqueous solutions of a triblock copolymer of ethylene oxide and 1,2-butylene oxide, E64B20E64 [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2003
Block copolymer E64B20E64, where E denotes oxyethylene, OCH2CH2, B denotes oxybutylene, OCH2CH (C2H5), and the subscripts denote number-average block lengths in repeat units, was synthesized by sequential anionic polymerization.
Colin Booth, Proespichaya Kanatharana, Chiraphon Chaibundit   +2 more
doaj