Results 251 to 260 of about 202,074 (291)

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Panoptic segmentation for complete labeling of fruit microstructure in 3D micro-CT images with deep learning. [PDF]

Plant Phenomics
Van Doorselaer L, Verboven P, Nicolai B.
europepmc   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Deep learning-assisted CBCT segmentation provides reliable volumetric assessment of mandibular defects compared with micro-CT for 3D printing and surgical planning. [PDF]

Sci Rep
Shalalvand M, Haghanifar S, Moudi E, Bijani A.   +3 more
europepmc   +1 more source

In-vitro comparison of the marginal and internal fit of 3D-printed crown restorations produced using different intraoral scanners and resin types: A Micro-CT analysis. [PDF]

BMC Oral Health
Yildirim B, Arslan E.
europepmc   +1 more source

Shaping ability of WaveOne Gold, hyflexEDM, trunatomy NiTi files: a micro-CT study. [PDF]

BMC Oral Health
Aktaş S, Yeter KY.
europepmc   +1 more source

Bone Mass, Microarchitecture, and Morphometric Insights on a Right Unilateral Bifid Mandibular Condyle: A Micro-CT Analysis Report and Literature Review. [PDF]

Diagnostics (Basel)
Torres-Villar C, Pacheco Muñoz J, Maranillo E, Ottone NE.   +3 more
europepmc   +1 more source

Validation of a Micro-CT Approach for Characterization of Murine and Human Bone in Osteogenesis Imperfecta [PDF]

, 2010
Harris, Gerald, Jameson, John, Molthen, Robert, Slavens, Brooke, Smith, Peter   +4 more
core   +1 more source

Ready-to-use or Powder/Liquid Bioceramic Sealer: Micro-CT analysis of root canal filling removal according to ultrasonic agitation. [PDF]

J Clin Exp Dent
Feitosa MES, Limoeiro AG, de Oliveira-Neto RS, Luna-Cruz SM, Vivan RR, Alcalde MP, Duarte MAH, de Vasconcelos BC.   +7 more
europepmc   +1 more source

Fine visualization of biological cells using X-ray micro-CT with the slow freezing contrast improved method. [PDF]

Sci Rep
Yoneyama A, Kawamoto M, Yasuda M, Kodama T, Shiranita K, Baba R, Matsumoto Y, Lwin TT, Takeya S.   +8 more
europepmc   +1 more source