Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source
Micro-CT evaluation of MTA compaction techniques in 3D-printed teeth with simulated perforating internal root resorption: an in vitro study. [PDF]
Sarıyılmaz Ö +4 more
europepmc +1 more source
Efficacy of Beam-Hardening Correction for Vascular Morphometry Using 3D Conebeam Micro-CT [PDF]
Dawson, Christopher A. +3 more
core +1 more source
A dual‐network bFGF@CB‐gel integrates: i) ChSMA scaffold (mechanical support/BMSCs delivery); ii) BC carrier (sustained bFGF release via EGFL/Itga2b and COMP/PI3K/AKT for adhesion/osteogenesis); iii) bFGF/PI3K/AKT/eNOS for angiogenesis. This rational, synergistic design addresses CSD bone regeneration challenges.
Yunze Feng +12 more
wiley +1 more source
Micro-CT Analysis of Rodent Temporal Bones: Identifying Optimal Species for Otological Research. [PDF]
Daoudi H +8 more
europepmc +1 more source
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
3D morphological analysis of age and sex-related changes in human cortical bone remodeling spaces using micro-CT. [PDF]
Wei X, Loundagin LL, Cooper DML.
europepmc +1 more source
Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Evaluation of two cementation protocols for lithium disilicate crowns on zirconia one-piece implants: a micro-CT analysis of cement thickness, porosity, and excess. [PDF]
Bunjaku VA +4 more
europepmc +1 more source
Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman +15 more
wiley +1 more source

