Results 31 to 40 of about 95,278 (259)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Determining the Location of Shared Electric Micro-Mobility Stations in Urban Environment

Urban Science
Locating shared electric micro-mobility stations in urban environments involves balancing multiple objectives, including accessibility, profitability, sustainability, operational costs, and social considerations.
Ahmed Jaber, Huthaifa Ashqar, Bálint Csonka   +2 more
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Seamless Mobility Mechanisms for Micro Mobile MPLS

IEICE Transactions on Communications, 2009
Efficient mobility management is one of the most important challenges in mobile networks. Since roaming between wireless cells can cause long handoff latency and high packet loss, it can result in poor quality of services for delay-sensitive applications and for applications requiring reliable transmission.
SANGUANWONGTHONG, Tubtim, SAENGUDOMLERT, Poompat, TUBTIANG, Arnon   +2 more
openaire   +1 more source

Carboxylic‐Acid Functionalized Multiwalled Carbon Nanotube‐Alkane‐Based Resistive Temperature Sensor for Cold Chain Applications

Advanced Engineering Materials, EarlyView.
This study presents a reversible temperature sensor with high switching ratio, ∼103. The device is fabricated using PET‐ITO and carbon nanotube dispersions in alkane. Considering its application in cold chain logistics, a proof‐of‐concept with LED is showcased. Thus, a temperature drop below the threshold temperature (crystallization temperature of the
Sunil Kumar Behera, Philippe Marrec, A. Jorge Parola, Madalena Dionísio, Hugo Águas, Andreia F. M. Santos, Hamed Pourkheirollah, Donald Lupo, César A. T. Laia   +8 more
wiley   +1 more source

Spatial insights into micro-mobility safety: establishing optimal buffers for scooter crash predictions

Digital Transportation and Safety
Establishing comparison events/crashes is among the key challenges in safety analysis. This study proposes a spatial consideration for predicting scooter crashes using Utah's five years of crash data. It involves creating buffers ranging from 5 to 250 ft
Boniphace Kutela, Meshack P. Mihayo, Emmanuel Kidando, Tumlumbe Juliana Chengula, Sia M. Lyimo   +4 more
doaj   +1 more source

Effects of the COVID-19 pandemic on use and perception of shared e-scooters

Transportation Research Interdisciplinary Perspectives, 2023
Micro-mobility, such as electric scooters (e-scooters) and bicycles, has gained attraction in recent years by offering reduced emissions, decreased congestion, and improved public health.
Shiva Pourfalatoun, Erika E. Miller
doaj   +1 more source

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Estimation of Pedestrian Risk Level Using Context Features for Remote Monitoring Alert System of Autonomous Micro-Mobility Vehicles

IEEE Open Journal of Intelligent Transportation Systems
Smart cities utilize IoT and ICT technologies to optimize urban infrastructure, addressing challenges such as rapid urbanization, traffic congestion, and environmental impact.
Kenta Azuma, Ryoichi Shinkuma, Hayato Itsumi, Koichi Nihei, Takanori Iwai   +4 more
doaj   +1 more source