Results 111 to 120 of about 1,275,740 (271)

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

open access: yesAdvanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang   +10 more
wiley   +1 more source

Effects of Mo and C addition on the microstructure and corrosion behavior of FeNiCrAl duplex alloy

open access: yesJournal of Materials Research and Technology
Effects of Mo and C addition on the microstructural evolution and corrosion resistance in chloride solution of FeNiCrAl duplex alloy were investigated.
Fangqiang Ning   +6 more
doaj   +1 more source

Unsuccessful Coupling of Weakly Coordinating Anion–Based Mg Salts and Alkoxyalkylamine Solvents for Rechargeable Mg Battery Application: Trace Water‐Driven Interfacial Failure

open access: yesAdvanced Science, EarlyView.
Combining recently established two ground‐breaking concepts, the adoption of WCAs and the use of alkoxyalkylamine‐based solvents in electrolyte formulations for rechargeable magnesium metal batteries, has led to unexpectedly unsuccessful electrochemical Mg plating/stripping performance. Comprehensive experimental and computational analyses revealed the
Toshihiko Mandai   +4 more
wiley   +1 more source

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

open access: yesAdvanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang   +5 more
wiley   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang   +7 more
wiley   +1 more source

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

open access: yesAdvanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia   +10 more
wiley   +1 more source

Friction Characteristic Study on Flat Surface Embedded With Micro Pit

open access: yesFriction Characteristic Study on Flat Surface Embedded With Micro Pit
Mechanical systems are always deal with wear and friction as the liability. The basic principle of the mechanical system is the surface interaction between surfaces which have a frictional force resulting in fatigue and damage to the mechanical components. Lubricant is used to minimize friction in order to solve the problem.
openaire   +2 more sources

Friction–Adhesion Coupling Behavior of SBS-Modified Asphalt Pavement with Discontinuous Surface Texture

open access: yesLubricants
Pitting distress introduces discontinuous surface texture, thereby modifying the friction–adhesion coupling at the rubber–asphalt interface. This study systematically investigates the interfacial friction response of SBS-modified asphalt pavements with ...
Gang Li   +7 more
doaj   +1 more source

Bio‐Inspired Gradient Coatings Enhance the Leading Edge Erosion Resistance of Wind Blades

open access: yesAdvanced Science, EarlyView.
Rain‐induced erosion of the wind turbine blade leading edge poses a critical challenge to maintenance and operation. Here, we propose a bio‐inspired approach for erosion protection utilising a platelet‐reinforced polyurethane coating with a graded through‐thickness architecture.
Natalia Sofia Guevara‐Sotelo   +2 more
wiley   +1 more source

Design implications of matrix composition and micro-galvanic interactions governing corrosion behavior in Al–Zn–Mg–(Cu) alloys

open access: yesMaterials & Design
The effects of aging treatment and Cu addition on the corrosion behavior of Al–Zn–Mg alloys were systematically investigated via mechanical, electrochemical, and microstructural analyses.
Tomoyo Manaka   +7 more
doaj   +1 more source

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