Results 201 to 210 of about 7,706 (255)

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Influence of Airborne‐Particle Abrasion and Thermal Cycling on Enamel Bond Strength and Roughness of Lithium Disilicate Treated With a Self‐Etching Ceramic Primer

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This in vitro study investigated the effect of a self‐etching ceramic primer (Monobond Etch & Prime [MEP]), with or without aluminum oxide airborne‐particle abrasion, on the surface roughness, and microtensile bond strength (μTBS) of lithium disilicate bonded to enamel, compared with the conventional hydrofluoric acid plus silane (HF 
Gabriel Freitas Pereira, Maudiela Isabel Arita Torres, Nicole Escórcio de Meneses, Ana Carolina Lima Moreira, Raniel Fernandes Peixoto   +4 more
wiley   +1 more source

Clinical Study on the Efficacy of 35% Hydrogen Peroxide Gel According to Exposure Time (40 min vs. 20 min) by Spectrophotometry

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To analyze the chromatic effect on CIELAB coordinates and the clinical effectiveness of in‐office whitening treatment (perceptible changes) with 35% hydrogen peroxide (HP) gel according to the number of clinical sessions and exposure time (40 min vs. 20 min) in the three thirds of the tooth.
Trinidad Rincón, Maria Portillo Muñoz, Maria Lobato, Ana María Martín Casado, Laryssa Mylenna Madruga Barbosa, Alessandro Loguercio, Cristina Gómez‐Polo   +6 more
wiley   +1 more source

One‐Year Color Stability of a Reduced 37.5% Hydrogen Peroxide In‐Office Bleaching Protocol: A Randomized Clinical Trial

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This randomized clinical trial evaluated the one‐year color stability and patient satisfaction regarding dental esthetic improvement after 37.5% hydrogen peroxide (37.5HP) in‐office bleaching with a reduced application protocol. Materials and Methods Forty participants with a shade mean C2 or darker were randomly allocated into two ...
Mariana Evangelista Santos, Danielle Araújo Izídio Carvalho de Azevedo, Virgínia Feitosa Nogueira Rocha, Sônia Saeger Meireles   +3 more
wiley   +1 more source

Systematic Review Evaluating the Influence of Veneering Design on the Clinical Outcome of All‐Ceramic Implant‐Supported 3–4 Units and Full Arch Fixed Dental Prostheses

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective To systematically assess survival, failure, and complication rates of all‐ceramic implant‐supported monolithic and micro‐veneered FDPs (i‐FDPs) in partially/completely edentulous patients compared to veneered restorations. Materials and Methods An electronic search identified prospective clinical studies on all‐ceramic i‐FDPs with at
Shaza Bishti, Stefan Wolfart, Marcel Zwahlen, Lukas Waltenberger   +3 more
wiley   +1 more source

Effect of margin thickness and cement gap on the fabrication and fit accuracy of additively manufactured crowns in definitive resins with different filler content

Journal of Prosthodontics, EarlyView.
Abstract Purpose To evaluate how commercially available composite resins in varying filler content affect the fabrication and fit accuracy (trueness and precision) of additively manufactured (AM) definitive crowns with different margin thickness and cement gaps by comparing them to subtractively manufactured (SM) polymer‐infiltrated ceramic crowns ...
Mustafa Borga Dönmez, Gülce Çakmak, Çiğdem Kahveci, Amir H. Nejat, Burak Yilmaz, Pinar Altinci   +5 more
wiley   +1 more source

Araguainha Dome, Brazil: A polygonal impact structure due to a complex pre‐impact regional structural framework

Meteoritics &Planetary Science, EarlyView.
Abstract We investigated the structural framework of the north–northwestern Paraná Basin in Brazil to test whether the pre‐impact structures in this region may have had any influence on the first‐order formation and morphostructure of the Araguainha impact structure (AIS).
Renato B. Bernardes, Wolf U. Reimold, Roger L. Gibson, Julia B. Curto Ma, Adolfo B. Silva, Natalia Hauser   +5 more
wiley   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source