Results 11 to 20 of about 39,059 (218)

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]

, 2010
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Douglas, K.W., Green, R., Douglas, Kenneth W., Pollock, K.G.J., Pollock, Kevin G.J., Catlow, Jamie, Young, D., Catlow, J., Young, David, Green, Rachel   +9 more
core   +4 more sources

CHAPLE‐Like Enteropathy and Renal Microangiopathy in an Adult Patient With CD46 Deficiency [PDF]

J Clin Lab Anal
We report an adult patient with a homozygous CD46 variant presenting with lifelong protein‐losing enteropathy, intestinal lymphangiectasia, and CVID‐like hypogammaglobulinemia mimicking CHAPLE syndrome. Concurrent renal biopsy revealed PLA2R‐negative membranous nephropathy with chronic thrombotic microangiopathy, establishing multi‐organ complement ...
Erden B, Korkmaz P, Yazici H, Dirim A, Beşışık F, Kahveci N, Kilinc Z, Unal D, Yegit O, Kalaycı T, Hürdoğan Ö, Özlük Y, Büyük M, Gelincik A, Demir S.   +14 more
europepmc   +2 more sources

Diabetic microangiopathy in Type 1 (insulin-dependent) diabetic patients after successful pancreatic and kidney or solitary kidney transplantation [PDF]

, 1991
To evaluate the beneficial effect of pancreatic grafting on peripheral microcirculation and long-term clinical outcome, we compared data of 28 Type 1 (insulin-dependent) diabetic patients either given a pancreatic and kidney graft simultaneously or given
W. Land, Illner, Wolf-Dieter, R. Landgraf, D. Abendroth, Land, Walter, W. -D. Illner, Schmand, J., J. Schmand, Abendroth, D., Landgraf, R.   +9 more
core   +1 more source

Circulating Biomarkers to Predict Diabetic Retinopathy in Patients with Diabetic Kidney Disease

Vision, 2023
The purpose of this review is to outline the currently available circulating biomarkers to predict diabetic retinopathy (DR) in patients with diabetic kidney disease (DKD).
Jonny, Laurencia Violetta, Arief S. Kartasasmita, Rudi Supriyadi, Coriejati Rita   +4 more
doaj   +1 more source

Potential Benefit of Ruxolitinib in Suspected Ocular and Neurological Transplant-Associated Thrombotic Microangiopathy After Allogeneic Stem Cell Transplantation: A Case Report and Review. [PDF]

Clin Case Rep
ABSTRACT We describe a rare case of suspected delayed‐onset TA‐TMA with ocular and neurological involvement following allo‐HSCT. The condition was refractory to standard therapies; neurological improvement was temporally associated with ruxolitinib initiation, suggesting a possible GVHD overlap.
Pillet LM, Arandilla A, Sauvetre G, Goupillou P, Lefevre A, Grall M, Bonnevalle A, Bourre B, Penther D, Porcheron S, Jardin F, Alani M, Dubois S, Camus V.   +13 more
europepmc   +2 more sources

Effects of apolipoprotein E genotype on outcome after ischaemic stroke, intracerebral haemorrhage and subarachnoid haemorrhage [PDF]

, 2006
BackgroundRodent models of acute ischaemic stroke and head injury suggest that apolipoprotein E (APOE) genotype influences neuronal repair, regeneration and survival after brain injury.
Sudlow, C L M; id_orcid, Martinez-gonzalez, N A   +1 more
core   +1 more source

Features of the Pathogenetic Mechanisms of Regional Blood Flow Disturbances in Diabetic Foot Syndrome (Lliterature Review)

Mìžnarodnij Endokrinologìčnij Žurnal, 2015
Diabetes mellitus (DM) is recognized as one of the most important noninfectious disease in the world, the prevalence of which became pandemic. In the list of late complications of DM, diabetic foot syndrome is a leader, causing early disability and high ...
О.B. Rusak
doaj   +1 more source

Remote Diffusion-Weighted Imaging Lesions in Intracerebral Hemorrhage: Characteristics, Mechanisms, Outcomes, and Therapeutic Implications

Frontiers in Neurology, 2017
Spontaneous intracerebral hemorrhage (ICH) is one of the most fatal form of stroke, with high mortality and disability rate. Small diffusion-weighed imaging lesions are not rare to see in regions remote from the hematoma after ICH and have been generally
Xu-hua Xu, Xu-hua Xu, Ting Gao, Wen-ji Zhang, Lu-sha Tong, Feng Gao, Feng Gao   +6 more
doaj   +1 more source

A case of “smoldering” immune‐mediated thrombotic thrombocytopenic purpura manifesting as recurrent cardioembolic stroke

Clinical Case Reports, 2021
Prompt recognition and treatment for thrombotic thrombocytopenic purpura (TTP) are critical to prevent the irreversible manifestations of this rare and quickly fatal hematologic disorder.
Mark E. Pepin, Eyad Saca, Soo Y. Kwon, Jori May   +3 more
doaj   +1 more source

A rare sporadic case of C3 gene mutation in 5-month-old baby girl with atypical hemolytic uremic syndrome, with good prognosis

Journal of Applied Hematology, 2018
Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy representing A, p.(Asp1115Asn). The early recognition and administration of eculizumab are a lifesaving measure.
Abdullah A Baothman, Hani Almalki, Mohammed Almaghrabi   +2 more
doaj   +1 more source