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Thrombotic thrombocytopenic purpura

The American Journal of Medicine, 1957
A 40-year-old obese black woman has had weakness and epigastric pain for several weeks and diarrhea and vomiting for four days. She does not appear acutely ill; the physical examination is normal except for abdominal tenderness. Her hematocrit is 25 percent. The platelet count is 10,000 per cubic millimeter.
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Thrombotic thrombocytopenic purpura

Blood Coagulation & Fibrinolysis, 1992
Thrombotic thrombocytopenic purpura is an uncommon disorder, but it continues to be of considerable interest. The disease mechanisms are unclear and the aetiology is unknown. Perhaps most enigmatic of all, the mode of action of plasma therapy, which successfully induces remission in about two-thirds of cases, is wholly inexplicable. There are currently
W G, Murphy   +4 more
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Thrombotic Thrombocytopenic Purpura

Acta Medica Scandinavica, 1952
Abstract 1.1. The clinical and pathologic observations of two cases of thrombotic thrombocytopenic purpura are presented. 2.2. This condition is characterized by the clinical triad of (1) hemolytic anemia; (2) thrombocytopenic purpura and (3) mental and neurologic abnormalities which may be bizarre or transient.
F, RACKOW, L, STEINGOLD, J H F, WOOD
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Thrombotic thrombocytopenic purpura

Disease-a-Month, 2014
Moschowitz first described thrombotic thrombocytopenic purpura (TTP) in 1925 in a 16-yearold female who presented with fever, petechiae, and a microangiopathic hemolytic anemia. Autopsy examination at the time revealed hyaline thrombi in the vascular beds of many organs. By 1947, several more cases were described and Singer suggested the term TTP.
Albara, Said   +3 more
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Diagnostic accuracy of the PLASMIC score in patients with suspected thrombotic thrombocytopenic purpura: A systematic review and meta‐analysis

Transfusion, 2020
The PLASMIC score was developed to identify patients with thrombotic microangiopathy who are most likely to have immune thrombotic thrombocytopenic purpura (TTP) and benefit from therapeutic plasma exchange (TPE).
Koosha Paydary   +4 more
semanticscholar   +1 more source

Thrombotic Thrombocytopenic Purpura

JAMA: The Journal of the American Medical Association, 1991
CASE PRESENTATION —Charles T. Bingham III, MD A 27-YEAR-OLD man was transferred to The Johns Hopkins Hospital for evaluation of delirium. Five days prior to admission he had presented to another hospital with hematemesis and syncope. Esophagogastroduodenoscopy revealed the presence of a 0.5-cm gastric ulcer.
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Immune Thrombotic Thrombocytopenic Purpura: A Review.

Journal of the American Medical Association (JAMA)
Importance Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy that presents with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. Worldwide annual incidence of iTTP is 2 cases per million to 6
Allyson M. Pishko, Ang Li, Adam Cuker
semanticscholar   +1 more source

THROMBOTIC THROMBOCYTOPENIC PURPURA

Annals of Internal Medicine, 1953
Excerpt Thrombotic thrombocytopenic purpura is a rare disease of which only a few cases have been diagnosed ante mortem.4Because of the rarity of diagnosis, other than at the autopsy table, few lab...
W S, GREEN, T W, GREEN
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Thrombotic Thrombocytopenic Purpura

Thrombosis and Haemostasis, 1995
Recent studies indicate that CRTTP patients have excessive shear stress-induced platelet aggregation that is associated with the presence of ULvWF multimers in their plasma and increased vWF-binding to their platelets by flow cytometry. In these CRTTP patients, relapses, excessive shear-aggregation and the presence in their plasma of ULvWF forms are ...
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Thrombotic thrombocytopenic purpura in pregnancy

BJOG: An International Journal of Obstetrics & Gynaecology, 1982
Summary. A 20 week primigravida with intrauterine fetal death and the rare occurrence of thrombotic thrombocytopenic purpura (TTP) in pregnancy is presented. Aprotinin has been used to overcome uterine inertia non‐responsive to oxytocin stimulation. TTP was successfully treated with repeated plasmaphereses.
M, Atlas   +4 more
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