Hereditary thrombotic thrombocytopenic purpura
Haematologica, 2019 The first description of thrombotic thrombocytopenic purpura (TTP) by Moschowitz was published nearly 100 years ago.[1][1] This was likely to have been an immune-mediated TTP episode and the author described multi organs affected with worsening ...
Marie Scully
doaj +9 more sources
Thrombotic thrombocytopenic purpura. [PDF]
Blood, 2017 AbstractThrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi.
B. Joly, P. Coppo, A. Veyradier
semanticscholar +8 more sources
Thrombotic thrombocytopenic purpura: a Trojan horse of acute leukemia?: a case report [PDF]
Journal of Medical Case ReportsBackground Thrombotic thrombocytopenic purpura is a rare and life-threatening hematologic disorder. We present the case of a 66-year-old man who developed acquired thrombotic thrombocytopenic purpura as the first manifestation of acute myeloblastic ...
Bertha Maria Nassani +4 more
doaj +2 more sources
Thrombotic thrombocytopenic purpura in pregnancy: Lessons from a case series of three patients [PDF]
Journal of International Medical ResearchThrombotic thrombocytopenic purpura is a rare but life-threatening complication during pregnancy. Historically, maternal mortality exceeded 90% before the introduction of therapeutic plasma exchange, which remains the cornerstone of treatment.
Sarah A Elkourashy +4 more
doaj +2 more sources
Pathogenicity of Anti-ADAMTS13 Autoantibodies in Acquired Thrombotic Thrombocytopenic Purpura [PDF]
EBioMedicine, 2015 BACKGROUND: Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease in which anti-ADAMTS13 autoantibodies cause severe enzyme deficiency.
Rens de Groot +2 more
exaly +4 more sources
Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)? [PDF]
Thrombosis JournalWeise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease.
Alexander Laemmle, Bernhard Lämmle
doaj +2 more sources
THROMBOTIC THROMBOCYTOPENIC PURPURA
Eurasian Journal of Medicine, 2019 Thrombotic thrombocytopenic purpura is characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, neurologic abnormalities and renal dysfunction.The typical pathologic lesion, widespread hyalin oclusions in arterioller.
Ali Rıza Odabaş +2 more
doaj +5 more sources
Thrombotic Thrombocytopenic Purpura
Apollo Medicine, 2005 This overview summarizes the history of thrombotic thrombocytopenic purpura (TTP) from its initial recognition in 1924 as a most often fatal disease to the discovery in 1997 of ADAMTS-13 deficiency as a major risk factor for acute disease manifestation.
Salil Jain +3 more
doaj +4 more sources
Idiopathic combined, autoantibody-mediated ADAMTS-13/factor H deficiency in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in a 17-year-old woman: a case report [PDF]
Journal of Medical Case Reports, 2011 Introduction Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome is a life-threatening condition with various etiopathogeneses. Without therapy approximately 90% of all patients die from the disease. Case presentation We report the case of a 17-
Patschan Daniel +7 more
doaj +4 more sources