Results 41 to 50 of about 11,766 (177)

Rare Presentation of Refractory Thrombotic Thrombocytopenic Purpura: Jejunal Stricture

International Journal of Hematology-Oncology and Stem Cell Research, 2017
Thrombotic thrombocytopenic purpura is a rare thrombotic disease characterized by episodes of thrombocytopenia and microangiopathic hemolytic anemia due to disseminated microvascular thrombosis.
Prabath K. Abeysundara, Inoshi Atukorala, K. P. C. Dalpatadu, Karthiha Balendran, M. D. S. A. Dilrukshi, G M O Fernando   +5 more
doaj  

Clinical factors and biomarkers predict outcome in patients with immune-mediated thrombotic thrombocytopenic purpura

Haematologica, 2019
Immune-mediated thrombotic thrombocytopenic purpura is characterized by severe thrombocytopenia and microangiopathic hemolytic anemia. It is primarily caused by immunoglobin G type autoantibodies against ADAMTS13, a plasma metalloprotease that cleaves ...
Elizabeth M. Staley, Wenjing Cao, Huy P. Pham, Chong H. Kim, Nicole K. Kocher, Lucy Zheng, Radhika Gangaraju, Robin G. Lorenz, Lance A. Williams, Marisa B. Marques, X. Long Zheng   +10 more
doaj   +1 more source

Inherited thrombotic thrombocytopenic purpura

Haematologica, 2009
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder characterized by thrombocytopenia and microangiopathic hemolytic anemia accompanied by variable neurological dysfunction, renal failure and fever.[1][1] Lesions consist of vessel wall thickening (mainly arterioles ...
Miriam Galbusera, Marina Noris, Giuseppe Remuzzi   +2 more
doaj   +3 more sources

A Case of Longitudinal Extensive Transversal Myelitis in Patient With Neuromyelitis Optica Spectrum Disorder and Systemic Lupus Erythematosus

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune, demyelinating disorder of the central nervous system. Clinical manifestations include optic neuritis, longitudinally extensive transverse myelitis (LETM) involving three or more vertebral segments, and, in most cases, seropositivity for anti‐aquaporin‐4 antibodies (AQP4‐IgG).
Nikolina Pravdic, Marijana Goluza, Natasa Pejanovic Skobic, Davor Batinic, Jelena Zovko, Tanja Zovko, Anita Ivankovic, Inge Klupka Saric   +7 more
wiley   +1 more source

Diclofenac-induced thrombotic thrombocytopenic purpura with concomitant complement dysregulation: a case report and review of the literature

Journal of Medical Case Reports, 2019
Background Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome are two forms of thrombotic microangiopathies. They are characterized by severe thrombocytopenia, microangiopathic hemolysis, and thrombosis, leading to a systemic inflammatory ...
Jose Perez Lara, Yaneidy Santana, Maneesh Gaddam, Asghar Ali, Sandeep Malik, Misbahuddin Khaja   +5 more
doaj   +1 more source

Thrombotic Antiphospholipid Syndrome: A Long Term Follow‐up of Patients With Recurrent Pregnancy Loss and Antiphospholipid Antibodies From the APS 1994 Study

American Journal of Reproductive Immunology, Volume 96, Issue 1, July 2026.
ABSTRACT Problem There is a paucity of studies on the incidence and predictors of thrombotic antiphospholipid syndrome (APS) after pregnancy in patients with recurrent pregnancy loss (RPL) and antiphospholipid antibodies (aPL). This prospective study aimed to assess the long‐term prognosis, including the occurrence of thrombosis and associated risk ...
Minami Ashio, Tamao Kitaori, Yoshitaka Yano, Chihiro Banno, Shoko Ide, Hiroyuki Yoshihara, Shinobu Goto, Takahiro Otani, Mayumi Sugiura‐Ogasawara   +8 more
wiley   +1 more source

Thrombotic Thrombocytopenic Purpura in a Newborn [PDF]

Journal of Perinatology, 2003
This report describes a newborn who presented with hyperbilirubinemia and thrombocytopenia. The patient recovered after treatment with antibiotics, phototherapy, and a platelet transfusion. Analysis of the plasma von Willebrand factor-cleaving metalloprotease, ADAMTS13, revealed low protease activity in the patient and her two siblings, and a mild ...
Paul T, Jubinsky, Richard, Moraille, Han-Mou, Tsai   +2 more
openaire   +2 more sources

Clinical burden and healthcare resource use of congenital thrombotic thrombocytopenic purpura in England: A linked primary and secondary care data analysis

British Journal of Haematology, Volume 209, Issue 1, Page 248-256, July 2026.
Summary Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra rare haematological disorder. This study aimed to estimate the clinical burden, healthcare resource use (HCRU) and associated costs of cTTP in England using primary and secondary care data. A retrospective cohort study was undertaken using the Clinical Practice Research Datalink (
Erin Barker, Will Lester, Heather Riley, Monica Garrett, Amie Padhiar, Annie Berkley, Sudhakar Manne, Umesh Doobaree, Oliver Heard   +8 more
wiley   +1 more source

Platelet Transfusion Is Associated With Increased Thrombosis and In‐Hospital Mortality Among Patients Hospitalized With Platelet Consumptive Disorders

European Journal of Haematology, Volume 117, Issue 1, Page 245-257, July 2026.
ABSTRACT Background Platelet transfusion is commonly used to reduce bleeding risk in platelet consumptive disorders. However, platelets may also promote thromboinflammatory pathways, and contemporary data evaluating the association between platelet transfusion, thrombosis, and mortality in this population are limited.
Manas Pustake, Shubhangi Deoker, Veeravenkata Garikiparthy, Kunal Sharma, Lakshmi Kattamuri, Abhizith Deoker, Abhinav Deol   +6 more
wiley   +1 more source

Clinical predictors of mortality in immune thrombotic thrombocytopenic purpura: A National Inpatient Sample analysis

British Journal of Haematology, EarlyView.
Anand Shah, Christopher Chen, Ilana Pyatetsky, Shruti Chaturvedi, Ankit Shah   +4 more
wiley   +1 more source